Y1738_MYCTO
ID Y1738_MYCTO Reviewed; 94 AA.
AC P9WLS2; L0TA89; P64887; P71996;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 30.
DE RecName: Full=Uncharacterized protein MT1780;
GN OrderedLocusNames=MT1780;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
RN [2]
RP INDUCTION BY NITRIC OXIDE (NO); BY HYPOXIA; IN MOUSE MODEL AND DORMANCY
RP REGULON.
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12953092; DOI=10.1084/jem.20030205;
RA Voskuil M.I., Schnappinger D., Visconti K.C., Harrell M.I., Dolganov G.M.,
RA Sherman D.R., Schoolnik G.K.;
RT "Inhibition of respiration by nitric oxide induces a Mycobacterium
RT tuberculosis dormancy program.";
RL J. Exp. Med. 198:705-713(2003).
CC -!- INDUCTION: A member of the dormancy regulon. Induced in response to
CC reduced oxygen tension (hypoxia) and low levels of nitric oxide (NO).
CC {ECO:0000269|PubMed:12953092}.
CC -!- SIMILARITY: To M.tuberculosis Rv2632c. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK46053.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE000516; AAK46053.1; ALT_INIT; Genomic_DNA.
DR PIR; E70688; E70688.
DR RefSeq; WP_003408522.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WLS2; -.
DR SMR; P9WLS2; -.
DR EnsemblBacteria; AAK46053; AAK46053; MT1780.
DR GeneID; 45425711; -.
DR KEGG; mtc:MT1780; -.
DR PATRIC; fig|83331.31.peg.1910; -.
DR HOGENOM; CLU_1711193_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR Gene3D; 3.30.160.240; -; 1.
DR InterPro; IPR015057; Rv2632c-like.
DR InterPro; IPR038070; Rv2632c-like_sf.
DR Pfam; PF08962; DUF1876; 1.
DR SUPFAM; SSF143212; SSF143212; 1.
PE 2: Evidence at transcript level;
FT CHAIN 1..94
FT /note="Uncharacterized protein MT1780"
FT /id="PRO_0000427429"
SQ SEQUENCE 94 AA; 10606 MW; EEBDB97D099380AD CRC64;
MCGDQSDHVL QHWTVDISID EHEGLTRAKA RLRWREKELV GVGLARLNPA DRNVPEIGDE
LSVARALSDL GKRMLKVSTH DIEAVTHQPA RLLY