ID   Y173_TREPA              Reviewed;         227 AA.
AC   O83203;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Uncharacterized protein TP_0173;
GN   OrderedLocusNames=TP_0173;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65163.1; -; Genomic_DNA.
DR   PIR; B71358; B71358.
DR   RefSeq; WP_010881620.1; NC_000919.1.
DR   AlphaFoldDB; O83203; -.
DR   STRING; 243276.TPANIC_0172; -.
DR   EnsemblBacteria; AAC65163; AAC65163; TP_0173.
DR   KEGG; tpa:TP_0173; -.
DR   eggNOG; COG2199; Bacteria.
DR   HOGENOM; CLU_1219262_0_0_12; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..227
FT                   /note="Uncharacterized protein TP_0173"
FT                   /id="PRO_0000202205"
FT   TRANSMEM        13..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        155..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          192..227
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   227 AA;  25261 MW;  D2878E9B8E15FE3D CRC64;
     MYFAILGTMS RTCVRAYAVF AIAIMVLTVA WFAFSISQAI QRNTVGAQQR FAQVIRRIAP
     RVTSKRQLTD AEADFIQNLC KNDDLIMALN IFSNRVQLFS WTYDDLMFVA GGGSELVPRS
     SSLFIKIFSG RVPYQAKDEC LLFTAALRVL TPANIFFRGC VVFLVMLTLT ISSMVFLVIE
     YLSVRRFQCA QGDARPRPAG PQGTARSRTD EAQVSPGTPP ECPVSVF