CAPSD_TBSVB
ID CAPSD_TBSVB Reviewed; 388 AA.
AC P11795; Q9IW10;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 2.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Capsid protein;
DE AltName: Full=Coat protein;
DE AltName: Full=p41;
GN ORFNames=ORF2;
OS Tomato bushy stunt virus (strain BS-3) (TBSV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Tolucaviricetes;
OC Tolivirales; Tombusviridae; Procedovirinae; Tombusvirus.
OX NCBI_TaxID=12146;
OH NCBI_TaxID=4072; Capsicum annuum (Capsicum pepper).
OH NCBI_TaxID=3749; Malus.
OH NCBI_TaxID=3766; Pyrus (pears).
OH NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OH NCBI_TaxID=4111; Solanum melongena (Eggplant) (Aubergine).
OH NCBI_TaxID=29777; Tolmiea menziesii.
OH NCBI_TaxID=13305; Tulipa.
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Galetzka D., Russo M., Rubino L., Krczal G.;
RT "Molecular characterization of a tombusvirus associated with a disease of
RT statice (Goniolimon tataricum (L.) Boiss.).";
RL J. Plant Pathol. 82:151-155(2000).
RN [2]
RP PROTEIN SEQUENCE OF 2-388.
RX PubMed=6481803; DOI=10.1016/0022-2836(84)90045-7;
RA Hopper P., Harrison S.C., Sauer R.T.;
RT "Structure of tomato bushy stunt virus. V. Coat protein sequence
RT determination and its structural implications.";
RL J. Mol. Biol. 177:701-713(1984).
RN [3]
RP X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS).
RX PubMed=6644820; DOI=10.1016/s0022-2836(83)80314-3;
RA Olson A.J., Bricogne G., Harrison S.C.;
RT "Structure of tomato bushy stunt virus IV. The virus particle at 2.9-A
RT resolution.";
RL J. Mol. Biol. 171:61-93(1983).
RN [4]
RP X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS).
RX PubMed=19711552; DOI=10.1038/276368a0;
RA Harrison S.C., Olson A.J., Schutt C.E., Winkler F.K., Bricogne G.;
RT "Tomato bushy stunt virus at 2.9 A resolution.";
RL Nature 276:368-373(1978).
CC -!- FUNCTION: Capsid protein self-assembles to form an icosahedral capsid
CC with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180
CC capsid proteins.
CC -!- SUBUNIT: Homomultimer. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC -!- PTM: The N-terminus is blocked. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the icosahedral plant coat protein family.
CC {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Virus Particle ExploreR db; Note=Icosahedral capsid
CC structure;
CC URL="https://viperdb.scripps.edu/Info_Page.php?VDB=2tbv";
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DR EMBL; AJ271328; CAB66390.1; -; mRNA.
DR PIR; S07259; S07259.
DR PDB; 2TBV; X-ray; 2.90 A; A/B/C=2-388.
DR PDBsum; 2TBV; -.
DR SMR; P11795; -.
DR EvolutionaryTrace; P11795; -.
DR GO; GO:0039617; C:T=3 icosahedral viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 2.60.120.20; -; 1.
DR InterPro; IPR000937; Capsid_prot_S-dom_vir.
DR InterPro; IPR029053; Viral_coat.
DR Pfam; PF00729; Viral_coat; 1.
DR PRINTS; PR00233; ICOSAHEDRAL.
DR PROSITE; PS00555; ICOSAH_VIR_COAT_S; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Capsid protein; Direct protein sequencing; RNA-binding;
KW T=3 icosahedral capsid protein; Virion.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000255"
FT CHAIN 2..388
FT /note="Capsid protein"
FT /id="PRO_0000222866"
FT REGION 2..102
FT /note="R domain, interaction with RNA"
FT REGION 57..63
FT /note="Involved in encapsidation"
FT /evidence="ECO:0000250"
FT REGION 103..264
FT /note="S domain, virion shell"
FT REGION 265..388
FT /note="P domain, projecting"
FT CONFLICT 14
FT /note="I -> V (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 34..36
FT /note="HIS -> YIG (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 107
FT /note="T -> TG (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 131
FT /note="L -> S (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 148
FT /note="I -> L (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 163
FT /note="H -> D (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 249..250
FT /note="TN -> AD (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 254..259
FT /note="DVFISY -> ELFLAR (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 275..276
FT /note="TR -> SK (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 308
FT /note="V -> A (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 348
FT /note="A -> D (in Ref. 2; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 366..380
FT /note="TTGISSATVNVVRGT -> VSGVAAGILLVGRA (in Ref. 2; AA
FT sequence)"
FT /evidence="ECO:0000305"
FT STRAND 95..97
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 109..116
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 119..123
FT /evidence="ECO:0007829|PDB:2TBV"
FT TURN 124..126
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 134..136
FT /evidence="ECO:0007829|PDB:2TBV"
FT HELIX 145..147
FT /evidence="ECO:0007829|PDB:2TBV"
FT TURN 148..150
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 151..168
FT /evidence="ECO:0007829|PDB:2TBV"
FT HELIX 192..195
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 206..208
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 210..213
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 224..226
FT /evidence="ECO:0007829|PDB:2TBV"
FT TURN 231..234
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 240..245
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 247..249
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 251..263
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 272..276
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 280..283
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 292..294
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 304..308
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 310..319
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 325..331
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 333..340
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 343..345
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 347..355
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 360..365
FT /evidence="ECO:0007829|PDB:2TBV"
FT STRAND 371..376
FT /evidence="ECO:0007829|PDB:2TBV"
SQ SEQUENCE 388 AA; 40911 MW; 008DF490F253B79E CRC64;
MAMTTRNNNN VLAISKKQLG VLAASAAVGA LRNHISESSP ALLQSAVGLG KKALNKVRNR
RKQGNQQIIT HVGGVGGSIM APVAVSRQLV GSKPKFTGRT SGSVTVTHRE YLTQVNNSSG
FVVNGGIVGN LLQLNPSNGT LFSWLPAIAS NFDQYSFNSV VLHYVPLCGT TEVGRVALYF
DKDSQDPEPA DRVELANFGV LKETAPWAEA MLRIPTDKVK RYCNDSATVD QKLIDLGQLG
IATYGGAGTN AVGDVFISYS VTLYFPQPTN TLLSTRRLDL TGSLADATGP GYLVLTRTPT
VLTHTFRVTG TFNLSGGLRC LTSLTLGATG AVVINDILAI DNVGTASAYF LNCTVSSLPA
TVTFTTTGIS SATVNVVRGT RANVVNLL
