ID   Y174_RICPR              Reviewed;         722 AA.
AC   P81171; Q9ZDY9;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Uncharacterized peptidase RP174;
DE            EC=3.4.21.-;
GN   OrderedLocusNames=RP174;
OS   Rickettsia prowazekii (strain Madrid E).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=272947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Madrid E;
RX   PubMed=9823893; DOI=10.1038/24094;
RA   Andersson S.G.E., Zomorodipour A., Andersson J.O., Sicheritz-Ponten T.,
RA   Alsmark U.C.M., Podowski R.M., Naeslund A.K., Eriksson A.-S., Winkler H.H.,
RA   Kurland C.G.;
RT   "The genome sequence of Rickettsia prowazekii and the origin of
RT   mitochondria.";
RL   Nature 396:133-140(1998).
CC   -!- SIMILARITY: Belongs to the peptidase S9B family. {ECO:0000305}.
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DR   EMBL; AJ235270; CAA14641.1; -; Genomic_DNA.
DR   PIR; B71728; B71728.
DR   RefSeq; NP_220564.1; NC_000963.1.
DR   RefSeq; WP_004595908.1; NC_000963.1.
DR   AlphaFoldDB; P81171; -.
DR   SMR; P81171; -.
DR   STRING; 272947.RP174; -.
DR   ESTHER; ricpr-y174; S9N_PPCE_Peptidase_S9.
DR   PRIDE; P81171; -.
DR   EnsemblBacteria; CAA14641; CAA14641; CAA14641.
DR   GeneID; 57569302; -.
DR   KEGG; rpr:RP174; -.
DR   PATRIC; fig|272947.5.peg.179; -.
DR   eggNOG; COG1505; Bacteria.
DR   HOGENOM; CLU_011290_4_0_5; -.
DR   OMA; HKAYEDF; -.
DR   Proteomes; UP000002480; Chromosome.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR023302; Pept_S9A_N.
DR   InterPro; IPR001375; Peptidase_S9.
DR   InterPro; IPR002470; Peptidase_S9A.
DR   Pfam; PF00326; Peptidase_S9; 1.
DR   Pfam; PF02897; Peptidase_S9_N; 1.
DR   PRINTS; PR00862; PROLIGOPTASE.
DR   SUPFAM; SSF53474; SSF53474; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Protease; Reference proteome; Serine protease.
FT   CHAIN           1..722
FT                   /note="Uncharacterized peptidase RP174"
FT                   /id="PRO_0000122426"
FT   ACT_SITE        575
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        658
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        691
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   722 AA;  83547 MW;  07CB3CABE18BBAD9 CRC64;
     MKKIICYFTI ILLTFGIDAM EDNNKQIYNP KETKFLEEAA GAEALKWAKE RTNKTEKALQ
     AMQEYKRIKK EIESIFYDQR KTLYGVIRKG YVYNFWMDDK NPQGLWRRTL VDNYYKDKPN
     WEVLIDFDKL SKKIGKKVAY RGVSNCVQNP NRYLISMSFG GKDEMFFREW DLEKKDFVKN
     GFEPITSCGK LLEGKFTYPT WVNKDTIIFN PVLYKDEITS SLYPNSLYIW KRGEAIEKAR
     KLFEVPKEYI RVSADKLLSD AISSSLIFIS ADKDFYNYDN YILDTQDKNF KLQKINMPSD
     ATLQGSFKEY VFWLLRSDWK FKNHNIKAGS LVALHFTDLL KAESDKTSLK ILFTPTENEV
     FNFIGTTKDR VFLATYDNVV SKVVTFTLEN EQWTKPVILK LPYQNAIFRM SSYEDEEEAL
     ITIENAIVPP TIYLWVKTHE LKVIRKALYS FDSENYVLEQ KEATSFDGVK IPYFIVYKKG
     IKFDGKNPTL LEAYGGFQVI NSPYFSRIKN EVWVKNGGVS VLANIRGGGE FGPEWHKAAQ
     GIKRQTAFND FFAVSEELIK QNITSPEYLG IKGGSNGGLL VSVAMTQRPE LFGAIACEVP
     ILDMIRYKEF GAGNSWVTEY GDPEIPNDLL HIKKYAPLEN LSLTQKYPTV LITDSVLDQR
     VHPWHGRIFE YVLAQNPNTK TYFLESRDSG HSSGSDLKES ANYFINLYTF FANTLKLKLI
     KF