ID   CAPSD_TGMVY             Reviewed;         247 AA.
AC   P03560;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   12-AUG-2020, entry version 86.
DE   RecName: Full=Capsid protein;
DE   AltName: Full=Coat protein;
DE            Short=CP;
GN   ORFNames=AR1, AV1;
OS   Tomato golden mosaic virus (strain Yellow vein) (TGMV).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC   Geplafuvirales; Geminiviridae; Begomovirus.
OX   NCBI_TaxID=223341;
OH   NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=16453557; DOI=10.1002/j.1460-2075.1984.tb02114.x;
RA   Hamilton W.D.O., Stein V.E., Coutts R.H.A., Buck K.W.;
RT   "Complete nucleotide sequence of the infectious cloned DNA components of
RT   tomato golden mosaic virus: potential coding regions and regulatory
RT   sequences.";
RL   EMBO J. 3:2197-2205(1984).
CC   -!- FUNCTION: Encapsidates the viral DNA into characteristic twinned
CC       ('geminate') particles. Binds the genomic viral ssDNA and shuttles it
CC       into and out of the cell nucleus. The CP of bipartite geminiviruses is
CC       not required for cell-to-cell or systemic movement.
CC   -!- SUBUNIT: Homomultimer. Binds to single-stranded and double-stranded
CC       viral DNA. Interacts (via nuclear localization signals) with host
CC       importin alpha-1a (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Host nucleus {ECO:0000250}.
CC       Note=It is actively transported into the host cell nucleus. It may be
CC       exported out of the nucleus through a nuclear export signal for cell-
CC       to-cell movement and spread (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the geminiviridae capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; K02029; AAA46582.1; -; Genomic_DNA.
DR   PIR; A04163; QQCVR1.
DR   RefSeq; NP_041238.1; NC_001507.1.
DR   SMR; P03560; -.
DR   GeneID; 956402; -.
DR   KEGG; vg:956402; -.
DR   Proteomes; UP000007405; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0039615; C:T=1 icosahedral viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.20; -; 1.
DR   InterPro; IPR000650; Gem_coat_AR1.
DR   InterPro; IPR000263; GV_A/BR1_coat.
DR   InterPro; IPR029053; Viral_coat.
DR   Pfam; PF00844; Gemini_coat; 1.
DR   PRINTS; PR00224; GEMCOATAR1.
DR   PRINTS; PR00223; GEMCOATARBR1.
PE   3: Inferred from homology;
KW   Capsid protein; DNA-binding; Host nucleus; Host-virus interaction;
KW   Metal-binding; Reference proteome; T=1 icosahedral capsid protein;
KW   Viral penetration into host nucleus; Virion; Virus entry into host cell;
KW   Zinc; Zinc-finger.
FT   CHAIN           1..247
FT                   /note="Capsid protein"
FT                   /id="PRO_0000222192"
FT   MOTIF           3..20
FT                   /note="Bipartite nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   MOTIF           31..45
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   MOTIF           92..113
FT                   /note="Nuclear export signal"
FT                   /evidence="ECO:0000255"
FT   MOTIF           191..238
FT                   /note="Bipartite nuclear localization signal"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   247 AA;  28684 MW;  CAF3B1948AFE115F CRC64;
     MPKRDAPWRL MAGTSKVSRS ANYSPRGSLP KRDAWVNRPM YRKPRIYRSL RGPDVPKGCE
     GPCKVQSYEQ RHDISLVGKV MCISDVTRGN GITHRVGKRF CVKSVYILGK IWMDENIKLK
     NHTNSVMFWL VRDRRPYGTP MDFGQVFNMF DNEPSTATVK NDLRDRFQVI HRFHAKVTGG
     QYASNEQALV RRFWKVNNNV VYNHQEAGKY ENHTENALLL YMACTHASNP VYATLKIRIY
     FYDSITN