CAPSD_TMGMV
ID CAPSD_TMGMV Reviewed; 159 AA.
AC P03579;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 02-JUN-2021, entry version 99.
DE RecName: Full=Capsid protein;
DE AltName: Full=Coat protein;
GN Name=CP;
OS Tobacco mild green mosaic virus (TMGMV) (TMV strain U2).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Martellivirales; Virgaviridae; Tobamovirus.
OX NCBI_TaxID=12241;
OH NCBI_TaxID=4072; Capsicum annuum (Capsicum pepper).
OH NCBI_TaxID=43071; Eryngium planum.
OH NCBI_TaxID=4090; Nicotiana glauca (Glaucous tobacco) (Tree tobacco).
OH NCBI_TaxID=4097; Nicotiana tabacum (Common tobacco).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2371769; DOI=10.1016/0042-6822(90)90520-2;
RA Solis I., Garcia-Arenal F.;
RT "The complete nucleotide sequence of the genomic RNA of the tobamovirus
RT tobacco mild green mosaic virus.";
RL Virology 177:553-558(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC STRAIN=ATCC PV-228;
RX PubMed=1984654; DOI=10.1016/0042-6822(91)90036-b;
RA Nejidat A., Cellier F., Holt C.A., Gafny R., Eggenberger A.L., Beachy R.N.;
RT "Transfer of the movement protein gene between two tobamoviruses: influence
RT on local lesion development.";
RL Virology 180:318-326(1991).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC STRAIN=TMGMVCPR-22;
RX PubMed=10675395; DOI=10.1099/0022-1317-81-3-577;
RA Bodaghi S., Ngon A Yassi M., Dodds J.A.;
RT "Heterogeneity in the 3'-terminal untranslated region of tobacco mild green
RT mosaic tobamoviruses from Nicotiana glauca resulting in variants with three
RT or six pseudoknots.";
RL J. Gen. Virol. 81:577-586(2000).
RN [4]
RP PROTEIN SEQUENCE OF 2-62 AND 136-159.
RX PubMed=4381390;
RA Wittmann H.G.;
RT "Primary protein structure of strains of tobacco mosaic virus. IV. Amino
RT acid sequences (1 to 61 and 135 to 158) of proteins of tobacco mosaic virus
RT strain U2.";
RL Z. Naturforsch. B 20:1213-1223(1965).
RN [5]
RP PROTEIN SEQUENCE OF 63-135.
RX PubMed=5586539; DOI=10.1007/bf00425778;
RA Rentschler L.;
RT "Amino acid sequence and physico-chemical behavior of coat proteins of wild
RT strain tobacco mosaic virus. I. Analysis of primary structure (pos. 62-134)
RT of coat proteins of wild strain U2.";
RL Mol. Gen. Genet. 100:84-95(1967).
RN [6]
RP X-RAY CRYSTALLOGRAPHY (3.5 ANGSTROMS).
RX PubMed=1453461; DOI=10.1016/0022-2836(92)90839-c;
RA Pattanayek R., Stubbs G.;
RT "Structure of the U2 strain of tobacco mosaic virus refined at 3.5-A
RT resolution using X-ray fiber diffraction.";
RL J. Mol. Biol. 228:516-528(1992).
CC -!- FUNCTION: Capsid protein self-assembles to form rod-shaped virions
CC about 18 nm in diameter with a central canal enclosing the viral
CC genomic RNA.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the virgaviridae capsid protein family.
CC {ECO:0000305}.
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DR EMBL; M34077; AAA47937.1; -; Genomic_RNA.
DR EMBL; M34236; AAA47939.1; -; Genomic_RNA.
DR EMBL; AF132907; AAD41791.1; -; Genomic_RNA.
DR PIR; C35520; VCTMUT.
DR RefSeq; NP_062916.1; NC_001556.1.
DR PDB; 1VTM; Fiber; 3.50 A; P=2-159.
DR PDBsum; 1VTM; -.
DR SMR; P03579; -.
DR GeneID; 1494073; -.
DR KEGG; vg:1494073; -.
DR EvolutionaryTrace; P03579; -.
DR Proteomes; UP000000281; Genome.
DR GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.120.70; -; 1.
DR InterPro; IPR001337; TMV-like_coat.
DR InterPro; IPR036417; TMV-like_coat_sf.
DR Pfam; PF00721; TMV_coat; 1.
DR SUPFAM; SSF47195; SSF47195; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Capsid protein; Direct protein sequencing;
KW Helical capsid protein; Virion.
FT INIT_MET 1
FT /note="Removed; by host"
FT /evidence="ECO:0000269|PubMed:4381390"
FT CHAIN 2..159
FT /note="Capsid protein"
FT /id="PRO_0000144945"
FT CONFLICT 23
FT /note="Q -> E (in Ref. 4; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 56..58
FT /note="VPS -> SPV (in Ref. 4; AA sequence)"
FT /evidence="ECO:0000305"
FT CONFLICT 101..112
FT /note="PAPNTTEIVNAT -> ABPTTAVPIBTZ (in Ref. 5; AA
FT sequence)"
FT /evidence="ECO:0000305"
FT TURN 8..10
FT /evidence="ECO:0007829|PDB:1VTM"
FT HELIX 11..14
FT /evidence="ECO:0007829|PDB:1VTM"
FT HELIX 22..24
FT /evidence="ECO:0007829|PDB:1VTM"
FT HELIX 25..31
FT /evidence="ECO:0007829|PDB:1VTM"
FT HELIX 39..52
FT /evidence="ECO:0007829|PDB:1VTM"
FT STRAND 59..61
FT /evidence="ECO:0007829|PDB:1VTM"
FT STRAND 69..74
FT /evidence="ECO:0007829|PDB:1VTM"
FT HELIX 77..87
FT /evidence="ECO:0007829|PDB:1VTM"
FT TURN 98..101
FT /evidence="ECO:0007829|PDB:1VTM"
FT STRAND 106..110
FT /evidence="ECO:0007829|PDB:1VTM"
FT TURN 112..116
FT /evidence="ECO:0007829|PDB:1VTM"
FT HELIX 117..131
FT /evidence="ECO:0007829|PDB:1VTM"
FT STRAND 133..135
FT /evidence="ECO:0007829|PDB:1VTM"
FT HELIX 142..145
FT /evidence="ECO:0007829|PDB:1VTM"
SQ SEQUENCE 159 AA; 17590 MW; 7F0169830984069F CRC64;
MPYTINSPSQ FVYLSSAYAD PVQLINLCTN ALGNQFQTQQ ARTTVQQQFA DAWKPVPSMT
VRFPASDFYV YRYNSTLDPL ITALLNSFDT RNRIIEVDNQ PAPNTTEIVN ATQRVDDATV
AIRASINNLA NELVRGTGMF NQAGFETASG LVWTTTPAT
