ID   Y1764_PYRFU             Reviewed;         225 AA.
AC   Q8U053;
DT   02-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=UPF0173 metal-dependent hydrolase PF1764 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=PF1764;
OS   Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=186497;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43587 / DSM 3638 / JCM 8422 / Vc1;
RX   PubMed=10430560; DOI=10.1093/genetics/152.4.1299;
RA   Maeder D.L., Weiss R.B., Dunn D.M., Cherry J.L., Gonzalez J.M.,
RA   DiRuggiero J., Robb F.T.;
RT   "Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P.
RT   horikoshii inferred from complete genomic sequences.";
RL   Genetics 152:1299-1305(1999).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; AE009950; AAL81888.1; -; Genomic_DNA.
DR   RefSeq; WP_011012905.1; NZ_CP023154.1.
DR   AlphaFoldDB; Q8U053; -.
DR   SMR; Q8U053; -.
DR   STRING; 186497.PF1764; -.
DR   PRIDE; Q8U053; -.
DR   EnsemblBacteria; AAL81888; AAL81888; PF1764.
DR   GeneID; 41713582; -.
DR   KEGG; pfu:PF1764; -.
DR   PATRIC; fig|186497.12.peg.1835; -.
DR   eggNOG; arCOG00497; Archaea.
DR   HOGENOM; CLU_070010_4_0_2; -.
DR   OMA; WHGHSTW; -.
DR   OrthoDB; 76909at2157; -.
DR   PhylomeDB; Q8U053; -.
DR   Proteomes; UP000001013; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..225
FT                   /note="UPF0173 metal-dependent hydrolase PF1764"
FT                   /id="PRO_0000156400"
SQ   SEQUENCE   225 AA;  24512 MW;  9C0874E28AB8076B CRC64;
     MVKVTFLGHA AFYIEGSKKI LIDPFLSGNP VASAKPDDFK SVDLILVTHA HGDHLGDVGT
     IAKRTGAKVV AMYDLANYIA EKYKGVETIG MNYGPTKVDE VEIVQVPAWH SSSDGKYSIG
     NACGYIVKLD GVTIYHAGDT YVFKDMELFA ELYGPIDVAL LPIGGHFTMG VREAAKAVEL
     LKPRHVIPMH YNTWPPIAAD PEEFKKLVGE KAKVVILKPG ESLEL