ID   Y1785_STAAR             Reviewed;         229 AA.
AC   Q6GG00;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=UPF0173 metal-dependent hydrolase SAR1785 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=SAR1785;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; BX571856; CAG40776.1; -; Genomic_DNA.
DR   RefSeq; WP_000777184.1; NC_002952.2.
DR   AlphaFoldDB; Q6GG00; -.
DR   SMR; Q6GG00; -.
DR   KEGG; sar:SAR1785; -.
DR   HOGENOM; CLU_070010_4_1_9; -.
DR   OMA; WHGHSTW; -.
DR   OrthoDB; 767622at2; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..229
FT                   /note="UPF0173 metal-dependent hydrolase SAR1785"
FT                   /id="PRO_0000156380"
SQ   SEQUENCE   229 AA;  25323 MW;  EE54D18179190E5A CRC64;
     MKLSFHGQST IYLEGNNKKV IVDPFISNNP KCDLNIETVQ VDYIVLTHGH FDHFGDVVEL
     AKKTEATVIG SAEMADYLSS YHGVENVHGM NIGGKANFDF GSVKFVQAFH SSSFTHENGI
     PVYLGMPMGI VFEVEGKTIY HTGDTGLFSD MSLIAKRHPV DVCFVPIGDN FTMGIDDASY
     AINEFIKPKI SVPIHYDTFP LIEQDPQQFK DAVNVGDVQI LKPGESVQF