ID   Y178_ALKPO              Reviewed;         385 AA.
AC   Q04454; D3FU45;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   15-JUN-2010, sequence version 2.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Putative transport protein BpOF4_00890;
DE   AltName: Full=ORF2;
GN   OrderedLocusNames=BpOF4_00890;
OS   Alkalihalophilus pseudofirmus (strain ATCC BAA-2126 / JCM 17055 / OF4)
OS   (Bacillus pseudofirmus).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalophilus.
OX   NCBI_TaxID=398511;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7678007; DOI=10.1016/s0021-9258(18)54205-8;
RA   Quirk P.G., Hicks D.B., Krulwich T.A.;
RT   "Cloning of the cta operon from alkaliphilic Bacillus firmus OF4 and
RT   characterization of the pH-regulated cytochrome caa3 oxidase it encodes.";
RL   J. Biol. Chem. 268:678-685(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-2126 / JCM 17055 / OF4;
RX   PubMed=21951522; DOI=10.1111/j.1462-2920.2011.02591.x;
RA   Janto B., Ahmed A., Ito M., Liu J., Hicks D.B., Pagni S., Fackelmayer O.J.,
RA   Smith T.A., Earl J., Elbourne L.D., Hassan K., Paulsen I.T., Kolsto A.B.,
RA   Tourasse N.J., Ehrlich G.D., Boissy R., Ivey D.M., Li G., Xue Y., Ma Y.,
RA   Hu F.Z., Krulwich T.A.;
RT   "Genome of alkaliphilic Bacillus pseudofirmus OF4 reveals adaptations that
RT   support the ability to grow in an external pH range from 7.5 to 11.4.";
RL   Environ. Microbiol. 13:3289-3309(2011).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86)
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ADC48247.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; M94110; AAA22369.1; -; Genomic_DNA.
DR   EMBL; CP001878; ADC48247.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; Q04454; -.
DR   STRING; 398511.BpOF4_00890; -.
DR   TCDB; 2.A.86.1.3; the autoinducer-2 exporter (ai-2e) family (formerly the perm family, tc #9,b,22).
DR   EnsemblBacteria; ADC48247; ADC48247; BpOF4_00890.
DR   KEGG; bpf:BpOF4_00890; -.
DR   eggNOG; COG0628; Bacteria.
DR   HOGENOM; CLU_031275_4_0_9; -.
DR   Proteomes; UP000001544; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR002549; AI-2E-like.
DR   InterPro; IPR014227; YtvI-like.
DR   PANTHER; PTHR21716; PTHR21716; 1.
DR   Pfam; PF01594; AI-2E_transport; 1.
DR   TIGRFAMs; TIGR02872; spore_ytvI; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..385
FT                   /note="Putative transport protein BpOF4_00890"
FT                   /id="PRO_0000148305"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        276..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        350..370
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        177
FT                   /note="S -> R (in Ref. 1; AAA22369)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   385 AA;  43341 MW;  398DCBF64A95D25B CRC64;
     MNKVNKINAY TCSSFQLHTI MKISFYVVER GFELAAFFTR RTIWIIISIL LFLVAAYFIL
     PVSLPLVAAL LTALILTPAV NALQRKTKIK RNVAVMLVFT VFVVFIGLSG YYIATKAITQ
     GTQIVENSPQ YISDINRAWL NFQRNLEEKY ENLPPELVQE INITVTNTLS DLRSNISDRN
     LIQDITSLIS SIPGYLVTFL VYLIALFLFM LELPRLREKL YSYLSERTKE KVNFMTSRLS
     YVIWGFFKAQ FLVSIIIFIV TLIGLLFIAP EVALLMAFII WLIDFVPIIG SIVILAPWAI
     FQLIVGDVST GSKLLILAAV LLIIRRTVEP KVMGKHIGLS PLATLIAMYL GLMLFGVIGF
     IIGPLLVIAF TSAKEAGIIK LNFKL