ID   Y178_UREPA              Reviewed;         126 AA.
AC   Q9PQW5;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Putative phosphotransferase enzyme IIB component UU178;
DE            EC=2.7.1.-;
DE   AltName: Full=Putative PTS system EIIB component;
GN   OrderedLocusNames=UU178;
OS   Ureaplasma parvum serovar 3 (strain ATCC 700970).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Ureaplasma.
OX   NCBI_TaxID=273119;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700970;
RX   PubMed=11048724; DOI=10.1038/35037619;
RA   Glass J.I., Lefkowitz E.J., Glass J.S., Heiner C.R., Chen E.Y.,
RA   Cassell G.H.;
RT   "The complete sequence of the mucosal pathogen Ureaplasma urealyticum.";
RL   Nature 407:757-762(2000).
CC   -!- FUNCTION: The phosphoenolpyruvate-dependent sugar phosphotransferase
CC       system (PTS), a major carbohydrate active -transport system, catalyzes
CC       the phosphorylation of incoming sugar substrates concomitant with their
CC       translocation across the cell membrane. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DOMAIN: The EIIB domain is phosphorylated by phospho-EIIA on a
CC       cysteinyl or histidyl residue, depending on the transported sugar.
CC       Then, it transfers the phosphoryl group to the sugar substrate
CC       concomitantly with the sugar uptake processed by the EIIC domain.
CC   -!- SIMILARITY: To M.genitalium MG129 and M.pneumoniae MPN268.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF222894; AAF30585.1; -; Genomic_DNA.
DR   RefSeq; WP_006688859.1; NC_002162.1.
DR   AlphaFoldDB; Q9PQW5; -.
DR   SMR; Q9PQW5; -.
DR   STRING; 273119.UU178; -.
DR   EnsemblBacteria; AAF30585; AAF30585; UU178.
DR   GeneID; 29672183; -.
DR   KEGG; uur:UU178; -.
DR   eggNOG; COG1264; Bacteria.
DR   HOGENOM; CLU_162090_0_0_14; -.
DR   OMA; WLYWRIK; -.
DR   Proteomes; UP000000423; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1360.60; -; 1.
DR   InterPro; IPR036878; Glu_permease_IIB.
DR   InterPro; IPR001996; PTS_IIB_1.
DR   SUPFAM; SSF55604; SSF55604; 1.
DR   PROSITE; PS51098; PTS_EIIB_TYPE_1; 1.
PE   3: Inferred from homology;
KW   Membrane; Phosphoprotein; Phosphotransferase system; Reference proteome;
KW   Transferase; Transmembrane; Transmembrane helix.
FT   CHAIN           1..126
FT                   /note="Putative phosphotransferase enzyme IIB component
FT                   UU178"
FT                   /id="PRO_0000210431"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          49..126
FT                   /note="PTS EIIB type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00421"
SQ   SEQUENCE   126 AA;  14318 MW;  3DB5414136906321 CRC64;
     MQNLNNKQKT LIIFLGIITF GIFIIYFFTK AKKVSQIRNT HLIVSSNIPF SLNDFYNCIG
     SKNNLVNVDA TINTLKIELK EINALNNEKL KVLGAKGIMC NQTKISIIFG DFCLELKELI
     KKDLFS