Y1808_MYCLE
ID Y1808_MYCLE Reviewed; 335 AA.
AC Q9CBL9;
DT 06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=UPF0353 protein ML1808 {ECO:0000255|HAMAP-Rule:MF_01340};
GN OrderedLocusNames=ML1808;
OS Mycobacterium leprae (strain TN).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=272631;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TN;
RX PubMed=11234002; DOI=10.1038/35059006;
RA Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA Barrell B.G.;
RT "Massive gene decay in the leprosy bacillus.";
RL Nature 409:1007-1011(2001).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01340};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01340}.
CC -!- SIMILARITY: Belongs to the UPF0353 family. {ECO:0000255|HAMAP-
CC Rule:MF_01340}.
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DR EMBL; AL583923; CAC30761.1; -; Genomic_DNA.
DR PIR; A87135; A87135.
DR RefSeq; NP_302229.1; NC_002677.1.
DR RefSeq; WP_010908550.1; NC_002677.1.
DR AlphaFoldDB; Q9CBL9; -.
DR SMR; Q9CBL9; -.
DR STRING; 272631.ML1808; -.
DR EnsemblBacteria; CAC30761; CAC30761; CAC30761.
DR KEGG; mle:ML1808; -.
DR PATRIC; fig|272631.5.peg.3433; -.
DR Leproma; ML1808; -.
DR eggNOG; COG2304; Bacteria.
DR HOGENOM; CLU_024570_2_0_11; -.
DR OMA; RYFRATD; -.
DR Proteomes; UP000000806; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 3.40.50.410; -; 1.
DR HAMAP; MF_01340; UPF0353; 1.
DR InterPro; IPR022933; UPF0353.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; SSF53300; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..335
FT /note="UPF0353 protein ML1808"
FT /id="PRO_0000057644"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT TRANSMEM 309..329
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT DOMAIN 98..294
FT /note="VWFA"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
SQ SEQUENCE 335 AA; 36100 MW; 674C99664F877580 CRC64;
MTLPLLGPMS LSGFEHSWFF LFIFIVFGLA AFYVMMQVAR QRRMLRFANM ELLESVAPNR
PVQWRHVPAI LLMLALLLFT IAMAGPTNDV RIPRNRAVVM LVIDVSQSMR ATDVEPNRMA
AAQEAAKQFA GELTPGINLG LIAYAGTATV LVSPTTNRYA TKNALDKLQF ADRTATGEAI
FTALQAIATV GAVIGGGEMP PPARIVLFSD GKETMPTNPD NPKGAYTAAR TAKDQGVPIS
TISFGTVYGF VEINGQRQPV PVDDETMKKV AQLSGGNSYN AATLAELKAV YASLQQQIGY
ETIKGDASAG WLRLGVLVLA LAALTALLIN RRLPT
