ID   CAPSD_TTVV1             Reviewed;         770 AA.
AC   Q9DHA8;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Probable capsid and replication-associated protein;
GN   ORFNames=ORF1;
OS   Torque teno virus (strain VT416) (TTV).
OC   Viruses; Anelloviridae; unclassified Anelloviridae.
OX   NCBI_TaxID=486280;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RX   PubMed=11024126; DOI=10.1128/jvi.74.21.9980-9986.2000;
RA   Kamahora T., Hino S., Miyata H.;
RT   "Three spliced mRNAs of TT virus transcribed from a plasmid containing the
RT   entire genome in COS1 cells.";
RL   J. Virol. 74:9980-9986(2000).
RN   [2]
RP   REVIEW.
RX   PubMed=17146841; DOI=10.1002/rmv.524;
RA   Hino S., Miyata H.;
RT   "Torque teno virus (TTV): current status.";
RL   Rev. Med. Virol. 17:45-57(2007).
CC   -!- FUNCTION: May self assemble to form an icosahedral capsid. Presumably
CC       essential to initiate and monitor viral genome replication by a rolling
CC       circle mechanism.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the anelloviridae capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; AB041007; BAB15944.1; -; Genomic_DNA.
DR   EMBL; AB041821; BAB15948.1; -; mRNA.
DR   RefSeq; NP_817122.1; NC_002076.2.
DR   SMR; Q9DHA8; -.
DR   PRIDE; Q9DHA8; -.
DR   GeneID; 1449575; -.
DR   KEGG; vg:1449575; -.
DR   Proteomes; UP000001448; Genome.
DR   GO; GO:0039615; C:T=1 icosahedral viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   InterPro; IPR004219; TTvirus_Unk.
DR   Pfam; PF02956; TT_ORF1; 1.
PE   2: Evidence at transcript level;
KW   Capsid protein; DNA replication; Reference proteome;
KW   T=1 icosahedral capsid protein; Virion.
FT   CHAIN           1..770
FT                   /note="Probable capsid and replication-associated protein"
FT                   /id="PRO_0000315326"
FT   REGION          647..682
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          697..717
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        659..676
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        700..717
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   770 AA;  90165 MW;  1BD91574BED7D602 CRC64;
     MAYGWWRRRR RRWRRWRRRP WRRRWRTRRR RPARRRGRRR NVRRRRRGGR WRRRYRRWKR
     KGRRRKKAKI IIRQWQPNYR RRCNIVGYIP VLICGENTVS RNYATHSDDT NYPGPLGGGM
     TTDKFTLRIL YDEYKRFMNY WTASNEDLDL CRYLGVNMYF FRHPDVDFII KINTMPPFLD
     TELTAPSIHP GMLALDKRAR WIPSLKSRPG KKHYIKIRVG APKMFTDKWY PQTDLCDMVL
     LTVYATAADM QYPFGSPLTD SVVVNFQVLQ SMYDQNISIL PDQKSEREKL LTQITDYIPF
     YNTTQTIAQL KPFIDAGNIT PNTPATTWGS YINTTKFTTA ATTTYTYPGT TTTTVTMLTC
     NDSWYRGTVY NDKIKNLPKQ AATLYSKATK TLLGNTFTTD DHTLEYHGGL YSSIWLSPGR
     SYFETTGAYT DIKYNPFTDR GEGNMLWIDW LSKKNMNYDK VQSKCLISDL PLWAAAYGYV
     EFCAKSTGDQ NIHMNARLLI RSPFTDPQLL VHTDPTKGFV PYSLNFGNGK MPGGSSNVPI
     RMRAKWYPTL FHQQEVLEAL AQSGPFAYHS DIKKVSLGMK YRFKWIWGGN PVRQQVVRNP
     CKETHSSGNR VPRSLQIVDP KYNSPELTFH TWDFRRGLFG PKAIQRMQQQ PTTTDIFSAG
     HKRPRRDTEV YHSSQEGEQK ESLLFPPVKL LRRVPPWEDS QQEESGSQSS EEETQTVSQQ
     LKQQLQQQRI LGVKLRLLFN QVQKIQQNQD INPTLLPRGG DLASLFQIAP