ID   Y1811_STAAS             Reviewed;         328 AA.
AC   Q6G845;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=UPF0421 protein SAS1811;
GN   OrderedLocusNames=SAS1811;
OS   Staphylococcus aureus (strain MSSA476).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282459;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MSSA476;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0421 family. {ECO:0000305}.
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DR   EMBL; BX571857; CAG43616.1; -; Genomic_DNA.
DR   RefSeq; WP_000999713.1; NC_002953.3.
DR   AlphaFoldDB; Q6G845; -.
DR   SMR; Q6G845; -.
DR   KEGG; sas:SAS1811; -.
DR   HOGENOM; CLU_067028_0_0_9; -.
DR   OMA; ANVMEEW; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010343; ArAE_1.
DR   Pfam; PF06081; ArAE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..328
FT                   /note="UPF0421 protein SAS1811"
FT                   /id="PRO_0000283020"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   328 AA;  37436 MW;  3AA90C796DF97494 CRC64;
     MNDQWYKHLI GARTIKTGIA IFLTAVFCMA LDLTPIYAIL TAVVTIEPTA KASLIKGYRR
     LPATVIGAGF AVLFTYLFGD QSPFTYALSA TFTILFCTKL KLQVGTNVAV LTSLAMIPGI
     HDAYIFNFLS RTLTAIIGLV TSGLINFMVF PPKYYGQVEE KLSKTDALMY KLFYNRCQEL
     ILSRLQSDKS EKAYKNIFNL NNQVETLISY QRDELSYHKK KECDWKLLNQ LTKRAYTNRL
     FITHLSNIIY LPKNTRVNFS GDEKMALLKI SSSIKDIFYD GSFKREDDSV ETLRSTIKAL
     EISGENQIKS HILYEVLMIY RLLDSRYA