Y1813_MYCTO
ID Y1813_MYCTO Reviewed; 143 AA.
AC P9WLS0; L0TAP3; P64889; Q50620;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 30.
DE RecName: Full=Uncharacterized protein MT1861;
DE Flags: Precursor;
GN OrderedLocusNames=MT1861;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
RN [2]
RP INDUCTION BY NITRIC OXIDE (NO) AND BY HYPOXIA, AND DORMANCY REGULON.
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12953092; DOI=10.1084/jem.20030205;
RA Voskuil M.I., Schnappinger D., Visconti K.C., Harrell M.I., Dolganov G.M.,
RA Sherman D.R., Schoolnik G.K.;
RT "Inhibition of respiration by nitric oxide induces a Mycobacterium
RT tuberculosis dormancy program.";
RL J. Exp. Med. 198:705-713(2003).
CC -!- INDUCTION: A member of the dormancy regulon. Induced in response to
CC reduced oxygen tension (hypoxia) and low levels of nitric oxide (NO).
CC {ECO:0000269|PubMed:12953092}.
CC -!- SIMILARITY: To M.tuberculosis Rv1269c. {ECO:0000305}.
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DR EMBL; AE000516; AAK46134.1; -; Genomic_DNA.
DR PIR; G70982; G70982.
DR RefSeq; WP_003409199.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WLS0; -.
DR SMR; P9WLS0; -.
DR EnsemblBacteria; AAK46134; AAK46134; MT1861.
DR GeneID; 45425788; -.
DR KEGG; mtc:MT1861; -.
DR PATRIC; fig|83331.31.peg.2004; -.
DR HOGENOM; CLU_150616_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR InterPro; IPR025240; DUF4189.
DR Pfam; PF13827; DUF4189; 1.
PE 2: Evidence at transcript level;
KW Signal.
FT SIGNAL 1..32
FT /evidence="ECO:0000255"
FT CHAIN 33..143
FT /note="Uncharacterized protein MT1861"
FT /id="PRO_0000427430"
SQ SEQUENCE 143 AA; 14981 MW; 7CEB0DA60F7981B2 CRC64;
MITNLRRRTA MAAAGLGAAL GLGILLVPTV DAHLANGSMS EVMMSEIAGL PIPPIIHYGA
IAYAPSGASG KAWHQRTPAR AEQVALEKCG DKTCKVVSRF TRCGAVAYNG SKYQGGTGLT
RRAAEDDAVN RLEGGRIVNW ACN