ID   Y1818_BACFR             Reviewed;         553 AA.
AC   Q64VB3;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Uncharacterized transporter BF1818;
GN   OrderedLocusNames=BF1818;
OS   Bacteroides fragilis (strain YCH46).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=295405;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YCH46;
RX   PubMed=15466707; DOI=10.1073/pnas.0404172101;
RA   Kuwahara T., Yamashita A., Hirakawa H., Nakayama H., Toh H., Okada N.,
RA   Kuhara S., Hattori M., Hayashi T., Ohnishi Y.;
RT   "Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions
RT   regulating cell surface adaptation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14919-14924(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC       {ECO:0000305}.
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DR   EMBL; AP006841; BAD48565.1; -; Genomic_DNA.
DR   RefSeq; WP_005786793.1; NZ_UYXF01000005.1.
DR   RefSeq; YP_099099.1; NC_006347.1.
DR   AlphaFoldDB; Q64VB3; -.
DR   SMR; Q64VB3; -.
DR   STRING; 295405.BF1818; -.
DR   EnsemblBacteria; BAD48565; BAD48565; BF1818.
DR   GeneID; 66329358; -.
DR   KEGG; bfr:BF1818; -.
DR   PATRIC; fig|295405.11.peg.1766; -.
DR   HOGENOM; CLU_035023_3_1_10; -.
DR   OMA; VYPLGMF; -.
DR   Proteomes; UP000002197; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; -; 2.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 2.
DR   SUPFAM; SSF116726; SSF116726; 2.
DR   TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 2.
DR   PROSITE; PS51202; RCK_C; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Repeat; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..553
FT                   /note="Uncharacterized transporter BF1818"
FT                   /id="PRO_0000208750"
FT   TRANSMEM        13..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        37..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        69..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        157..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        375..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        402..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        436..458
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        468..490
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        497..514
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        529..551
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          190..273
FT                   /note="RCK C-terminal 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
FT   DOMAIN          281..365
FT                   /note="RCK C-terminal 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ   SEQUENCE   553 AA;  59355 MW;  67843A6E8011CEA4 CRC64;
     MEWLYSLFIE HSALQAVVVL SLISAIGLGL GKIHVCGISL GVTFVFFAGI LAGHFGLSID
     PQMLNYAESF GLIIFVYALG LQVGPGFFSS FRKGGVTLNM LAIAVVILGT FLAVVCSYTT
     GVSLPNMVGI LCGATTNTPA LGAAQQTLKQ MGLESSTPAL GCAVAYPLGV IGVILAVLLI
     RKLLVRREDL EVQEKDDANK TYIAAFQVHN PAIFNKSIKD IAHMSYPKFV ISRLWRDGNV
     SIPTSEKIIK EGDRLLVVTS EKDALALTVL FGEQENTDWN KEDIDWNAID SQLISQRIVV
     TRPELNGKKL GALRLRNHYG INISRVYRSG VQLLATPELT LQLGDRLTVV GEAAAIQNVE
     KVLGNAIKSL KEPNLVAVFV GIILGLALGA VPFSIPGIST PVRLGLAGGP IIVGILIGTF
     GPRLHMITYT TRSANLMLRA LGLSLYLACL GLDAGAHFFD TVFRPEGLLW IGLGFGLTLV
     PTVLVGFFAF KIMKIDFGSV SGMLCGSMAN PMALNYANDT IPGDNPSVAY ATVYPLSMFL
     RVIIAQVLLM FLL