ID   Y181_TREPA              Reviewed;         147 AA.
AC   O83211;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Uncharacterized protein TP_0181;
GN   OrderedLocusNames=TP_0181;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65194.1; -; Genomic_DNA.
DR   PIR; G71353; G71353.
DR   RefSeq; WP_010881628.1; NC_021490.2.
DR   AlphaFoldDB; O83211; -.
DR   SMR; O83211; -.
DR   STRING; 243276.TPANIC_0181; -.
DR   EnsemblBacteria; AAC65194; AAC65194; TP_0181.
DR   GeneID; 57878719; -.
DR   KEGG; tpa:TP_0181; -.
DR   eggNOG; COG2919; Bacteria.
DR   HOGENOM; CLU_146778_0_0_12; -.
DR   OMA; ELMVINH; -.
DR   OrthoDB; 1677401at2; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007060; FtsL/DivIC.
DR   Pfam; PF04977; DivIC; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..147
FT                   /note="Uncharacterized protein TP_0181"
FT                   /id="PRO_0000202212"
FT   TRANSMEM        4..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        123..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   147 AA;  16464 MW;  F680BA906C6BEA77 CRC64;
     MRIYLRVVLP LSLALNSYGV LAFFWGERGV CAMRLLEREK KELVHHIQTL AERGRDLAAV
     VDALSFDEET IGAYARQLGY VRAGDVLVRP VNFTVAHMHT LDSGDARPLV APACFSDTRC
     KVYALCVGFF VVLLQLLWGS ARAYFKT