ID   CAPSD_TTVVG             Reviewed;         770 AA.
AC   Q9WGZ0;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Probable capsid and replication-associated protein;
GN   ORFNames=ORF1;
OS   Torque teno virus (isolate Human/Ghana/GH1/1996) (TTV).
OC   Viruses; Anelloviridae; unclassified Anelloviridae.
OX   NCBI_TaxID=487067;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10077657; DOI=10.1073/pnas.96.6.3177;
RA   Mushahwar I.K., Erker J.C., Muerhoff A.S., Leary T.P., Simons J.N.,
RA   Birkenmeyer L.G., Chalmers M.L., Pilot-Matias T.J., Dexai S.M.;
RT   "Molecular and biophysical characterization of TT virus: evidence for a new
RT   virus family infecting humans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 96:3177-3182(1999).
RN   [2]
RP   REVIEW.
RX   PubMed=17146841; DOI=10.1002/rmv.524;
RA   Hino S., Miyata H.;
RT   "Torque teno virus (TTV): current status.";
RL   Rev. Med. Virol. 17:45-57(2007).
CC   -!- FUNCTION: May self assemble to form an icosahedral capsid. Presumably
CC       essential to initiate and monitor viral genome replication by a rolling
CC       circle mechanism.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the anelloviridae capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF122913; AAD24198.1; -; Genomic_DNA.
DR   SMR; Q9WGZ0; -.
DR   Proteomes; UP000007550; Genome.
DR   GO; GO:0039615; C:T=1 icosahedral viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   InterPro; IPR004219; TTvirus_Unk.
DR   Pfam; PF02956; TT_ORF1; 1.
PE   3: Inferred from homology;
KW   Capsid protein; DNA replication; Reference proteome;
KW   T=1 icosahedral capsid protein; Virion.
FT   CHAIN           1..770
FT                   /note="Probable capsid and replication-associated protein"
FT                   /id="PRO_0000317471"
FT   REGION          645..682
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          697..717
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        659..676
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        700..717
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   770 AA;  89872 MW;  1F0481A8A9344763 CRC64;
     MAYGWWRRRR RRWRRWRRRP WRRRWRTRRR RPARRRGRRR NVRRRRRGGR WRRRYRRWKR
     KGRRRKKAKI IIRQWQPNYR RRCNIVGYIP VLICGENTVS RNYATHSDDT NYPGPFGGGM
     TTDKFTLRIL YGEYKRFMNY WTASNEDLDL CRYLGVNLYF FRHPDVDFII KINTMPPFLD
     TELTAPSIHP GMLALDKRAR WIPSLKSRPG KKHYIKIRVG APKMFTDKWY PQTDLCDMVL
     LTVYATAADM QYPFGSPLTD SVVVNFQVLQ SMYDEKISIL PDEKIQRQNL LTSISNYIPF
     YNTTQTIAQL KPFVDAGNAI SGTTTTTWGS LLNTTKFTTT TTTTYTYPGT TNTTVTFITA
     NDSWYRGTVY NQNIKDVAKK AAELYSKATK AVLGNTFTTE DYTLGYHGGL YSSIWLSPGR
     SYFETPGAYT DIKYNPFTDR GEGNMLWIDW LSKKNMNYDK VQSKCLISDL PLWAAAYGYV
     EFCAKSTGDQ NIHMNARLLI RSPFTDPQLL VHTDPTKGFV PYSLNFGNGK MPGGSSNVPI
     RMRAKWYPTL LHQQEVLEAL AQSGPFAYHA DIKKVSLGMK YRFKWIWGGN PVRQQVVRNP
     CKETHSSGNR VPRSLQIVDP KYNSPELTFH TWDFKRGLFG PKAIQRMQQQ PTTTDIFSAG
     RKRPRRDTEV YHSSQEGEQK ESLLFPPVKL LRRVPPWEDS QQEESGSQSS EEETQTVSQQ
     LKQQLQQQRI LGVKLRLLFN QVQKIQQNQD INPTLLPRGG DLASLFQIAP