ID   Y1825_MYCTO             Reviewed;         292 AA.
AC   P9WFG2; L0T9D2; P64895; Q50608;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=UPF0749 protein MT1873;
DE   Flags: Precursor;
GN   OrderedLocusNames=MT1873;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0749 family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK46146.1; -; Genomic_DNA.
DR   PIR; B70721; B70721.
DR   RefSeq; WP_003899038.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WFG2; -.
DR   SMR; P9WFG2; -.
DR   EnsemblBacteria; AAK46146; AAK46146; MT1873.
DR   GeneID; 45425799; -.
DR   KEGG; mtc:MT1873; -.
DR   PATRIC; fig|83331.31.peg.2017; -.
DR   HOGENOM; CLU_040273_0_2_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010273; DUF881.
DR   PANTHER; PTHR37313; PTHR37313; 1.
DR   Pfam; PF05949; DUF881; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..292
FT                   /note="UPF0749 protein MT1873"
FT                   /id="PRO_0000428544"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        229..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   292 AA;  30645 MW;  22B2DCED7ADCFCC7 CRC64;
     MSENRPEPVA AETSAATTAR HSQADAGAHD AVRRGRHELP ADHPRSKVGP LRRTRLTEIL
     RGGRSRLVFG TLAILLCLVL GVAIVTQVRQ TDSGDSLETA RPADLLVLLD SLRQREATLN
     AEVIDLQNTL NALQASGNTD QAALESAQAR LAALSILVGA VGATGPGVMI TIDDPGPGVA
     PEVMIDVINE LRAAGAEAIQ INDAHRSVRV GVDTWVVGVP GSLTVDTKVL SPPYSILAIG
     DPPTLAAAMN IPGGAQDGVK RVGGRMVVQQ ADRVDVTALR QPKQHQYAQP VK