ID   Y1839_STAAT             Reviewed;         374 AA.
AC   A8YY16;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=UPF0754 membrane protein USA300HOU_1839;
GN   OrderedLocusNames=USA300HOU_1839;
OS   Staphylococcus aureus (strain USA300 / TCH1516).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=451516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USA300 / TCH1516;
RX   PubMed=17986343; DOI=10.1186/1471-2180-7-99;
RA   Highlander S.K., Hulten K.G., Qin X., Jiang H., Yerrapragada S.,
RA   Mason E.O. Jr., Shang Y., Williams T.M., Fortunov R.M., Liu Y., Igboeli O.,
RA   Petrosino J., Tirumalai M., Uzman A., Fox G.E., Cardenas A.M., Muzny D.M.,
RA   Hemphill L., Ding Y., Dugan S., Blyth P.R., Buhay C.J., Dinh H.H.,
RA   Hawes A.C., Holder M., Kovar C.L., Lee S.L., Liu W., Nazareth L.V.,
RA   Wang Q., Zhou J., Kaplan S.L., Weinstock G.M.;
RT   "Subtle genetic changes enhance virulence of methicillin resistant and
RT   sensitive Staphylococcus aureus.";
RL   BMC Microbiol. 7:99-99(2007).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0754 family. {ECO:0000305}.
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DR   EMBL; CP000730; ABX29842.1; -; Genomic_DNA.
DR   RefSeq; WP_000992527.1; NC_010079.1.
DR   AlphaFoldDB; A8YY16; -.
DR   KEGG; sax:USA300HOU_1839; -.
DR   HOGENOM; CLU_042384_0_0_9; -.
DR   OMA; DTIMGSL; -.
DR   BioCyc; SAUR451516-HMP:GTV5-1871-MON; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007383; DUF445.
DR   InterPro; IPR016991; UCP032178.
DR   Pfam; PF04286; DUF445; 1.
DR   PIRSF; PIRSF032178; UCP032178; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..374
FT                   /note="UPF0754 membrane protein USA300HOU_1839"
FT                   /id="PRO_0000388316"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        354..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   374 AA;  42696 MW;  095EC493777FB6E4 CRC64;
     MNALFIIIFM IVVGAIIGGI TNVIAIRMLF HPFKPYYIFK FRVPFTPGLI PKRREEIATK
     IGQVIEEHLL TETLINEKLK SEQSQQAIES MIQQQLQKLT KDQLSIKQIT SQIDIDLEQV
     LQTNGNQYIE SQLNNYYTKH QNQTIASLLP NQLVTFLNQH VDNATDLLCD RARNYLSSAK
     GTQDINDMLD TFFNEKGKLI GMLQMFMTKE SIADRIQQEL IRLTSHPKAR TIVTSLITNE
     YQTFKDKPLN ELLDASQFNE IAENLSVYVT TYASKQANKP VVTLMPQFVD YLEGQLSSKL
     ANLIIEKLSI HLSTIMKKVD LRGLIEEQIN TFDLDYIEKL IIEIANKELK LIMSLGFILG
     GIIGFFQGLV AIFV