CAPSD_WDVS
ID CAPSD_WDVS Reviewed; 260 AA.
AC P06946;
DT 01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1988, sequence version 1.
DT 23-FEB-2022, entry version 83.
DE RecName: Full=Capsid protein;
DE AltName: Full=Coat protein;
DE Short=CP;
GN ORFNames=V1;
OS Wheat dwarf virus (isolate Sweden) (WDV).
OC Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC Geplafuvirales; Geminiviridae; Mastrevirus.
OX NCBI_TaxID=268789;
OH NCBI_TaxID=4498; Avena sativa (Oat).
OH NCBI_TaxID=4513; Hordeum vulgare (Barley).
OH NCBI_TaxID=4521; Lolium multiflorum (Italian ryegrass) (Lolium perenne subsp. multiflorum).
OH NCBI_TaxID=4550; Secale cereale (Rye).
OH NCBI_TaxID=4565; Triticum aestivum (Wheat).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=15938050; DOI=10.1002/j.1460-2075.1985.tb03912.x;
RA McDowell S.W., McDonald H., Hamilton W.D.O., Coutts R.H.A., Buck K.W.;
RT "The nucleotide sequence of cloned wheat dwarf virus DNA.";
RL EMBO J. 4:2173-2180(1985).
CC -!- FUNCTION: Encapsidates the viral genome into characteristic twinned
CC ('geminate') particles. Binds the genomic viral ssDNA and shuttles it
CC into and out of the cell nucleus. Plays a role in protection of the
CC genome from degradation, virus acquisition and transmission by insect
CC vectors, infectivity, and systemic movement. The CP of monopartite
CC geminiviruses is absolutely essential for virus movement (By
CC similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homomultimer. Interacts with the movement protein. Binds to
CC single-stranded and double-stranded viral DNA (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Host nucleus. Note=It is
CC actively transported into the host cell nucleus. It may be exported out
CC of the nucleus through a nuclear export signal for cell-to-cell
CC movement and spread (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the geminiviridae capsid protein family.
CC {ECO:0000305}.
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DR EMBL; X02869; CAA26622.1; -; Genomic_DNA.
DR PIR; A25005; VCCVWV.
DR SMR; P06946; -.
DR Proteomes; UP000007629; Genome.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0039615; C:T=1 icosahedral viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW.
DR Gene3D; 2.60.120.20; -; 1.
DR InterPro; IPR000143; Gemcoat_MSV.
DR InterPro; IPR000263; GV_A/BR1_coat.
DR InterPro; IPR029053; Viral_coat.
DR Pfam; PF00844; Gemini_coat; 1.
DR PRINTS; PR00223; GEMCOATARBR1.
DR PRINTS; PR00226; GEMCOATMSV.
PE 3: Inferred from homology;
KW Capsid protein; DNA-binding; Host nucleus; Reference proteome;
KW T=1 icosahedral capsid protein; Viral penetration into host nucleus;
KW Virion; Virus entry into host cell.
FT CHAIN 1..260
FT /note="Capsid protein"
FT /id="PRO_0000222199"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 10..36
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000250"
SQ SEQUENCE 260 AA; 29408 MW; 45A2FFEA8416FCF7 CRC64;
MVTNKDSRGK GKRKMEEGES SGRWKGAVYK RRKQAYKVVP VKPPALCVFR YNWLNSDRTN
IVVGNTPRVD LITCFAQGKA DNNRHTNQTV LYKFNIQGTC YMSDASAPFI GPVRLYHWLV
YDAEPKQAMP DATDIFTMPW NLLPSTWTVQ RAWSHRFVVK RKWTVNLVTD GRKVGSKTVD
QRYNWVVGKN IVDANKFFKG LRVTTEWMNT GDGKIGDIKK GALYLISSTR GGVTGDSAST
AFDVVCAYTH ACYFKAIGIQ
