ID   Y1854_MYCBO             Reviewed;         307 AA.
AC   P64892; A0A1R3XZF3; Q50610; X2BJ59;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=UPF0749 protein Mb1854;
DE   Flags: Precursor;
GN   OrderedLocusNames=BQ2027_MB1854;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0749 family. {ECO:0000305}.
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DR   EMBL; LT708304; SIU00458.1; -; Genomic_DNA.
DR   RefSeq; NP_855506.1; NC_002945.3.
DR   RefSeq; WP_003901262.1; NC_002945.4.
DR   AlphaFoldDB; P64892; -.
DR   SMR; P64892; -.
DR   EnsemblBacteria; SIU00458; SIU00458; BQ2027_MB1854.
DR   GeneID; 45425797; -.
DR   PATRIC; fig|233413.5.peg.2034; -.
DR   OMA; RVRDRDM; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010273; DUF881.
DR   PANTHER; PTHR37313; PTHR37313; 1.
DR   Pfam; PF05949; DUF881; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..307
FT                   /note="UPF0749 protein Mb1854"
FT                   /id="PRO_0000014111"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   307 AA;  31935 MW;  7F0BCD47FD2553A1 CRC64;
     MAESDRLLGG YDPNAGYSAH AGAQPQRIPV PSLLRALLSE HLDAGYAAVA AERERAAAPR
     CWQARAVSWM WQALAATLVA AVFAAAVAQA RSVAPGVRAA QQLLVASVRS TQAAATTLAQ
     RRSTLSAKVD DVRRIVLADD AEGQRLLARL DVLSLAAASA PVVGPGLTVT VTDPGASPNL
     SDVSKQRVSG SQQIILDRDL QLVVNSLWES GAEAISIDGV RIGPNVTIRQ AGGAILVDNN
     PTSSPYTILA VGPPHAMQDV FDRSAGLYRL RLLETSYGVG VSVNVGDGLA LPAGATRDVK
     FAKQIGP