ID   Y1856_MYCBO             Reviewed;         292 AA.
AC   P64896; A0A1R3XZG2; Q50608; X2BJA8;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=UPF0749 protein Mb1856;
DE   Flags: Precursor;
GN   OrderedLocusNames=BQ2027_MB1856;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0749 family. {ECO:0000305}.
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DR   EMBL; LT708304; SIU00460.1; -; Genomic_DNA.
DR   RefSeq; NP_855508.1; NC_002945.3.
DR   RefSeq; WP_003899038.1; NC_002945.4.
DR   AlphaFoldDB; P64896; -.
DR   SMR; P64896; -.
DR   EnsemblBacteria; SIU00460; SIU00460; BQ2027_MB1856.
DR   GeneID; 45425799; -.
DR   PATRIC; fig|233413.5.peg.2036; -.
DR   OMA; GLWPPRV; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010273; DUF881.
DR   PANTHER; PTHR37313; PTHR37313; 1.
DR   Pfam; PF05949; DUF881; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..292
FT                   /note="UPF0749 protein Mb1856"
FT                   /id="PRO_0000014113"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        229..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   292 AA;  30645 MW;  22B2DCED7ADCFCC7 CRC64;
     MSENRPEPVA AETSAATTAR HSQADAGAHD AVRRGRHELP ADHPRSKVGP LRRTRLTEIL
     RGGRSRLVFG TLAILLCLVL GVAIVTQVRQ TDSGDSLETA RPADLLVLLD SLRQREATLN
     AEVIDLQNTL NALQASGNTD QAALESAQAR LAALSILVGA VGATGPGVMI TIDDPGPGVA
     PEVMIDVINE LRAAGAEAIQ INDAHRSVRV GVDTWVVGVP GSLTVDTKVL SPPYSILAIG
     DPPTLAAAMN IPGGAQDGVK RVGGRMVVQQ ADRVDVTALR QPKQHQYAQP VK