ID   Y185_MYCGE              Reviewed;         701 AA.
AC   P47431; Q49380;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Uncharacterized lipoprotein MG185;
DE   Flags: Precursor;
GN   OrderedLocusNames=MG185;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 525-701.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=8524858; DOI=10.1073/pnas.92.25.11829;
RA   Peterson S.N., Bailey C.C., Jensen J.S., Borre M.B., King E.S., Bott K.F.,
RA   Hutchison C.A. III;
RT   "Characterization of repetitive DNA in the Mycoplasma genitalium genome:
RT   possible role in the generation of antigenic variation.";
RL   Proc. Natl. Acad. Sci. U.S.A. 92:11829-11833(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the MG185/MG260 family. {ECO:0000305}.
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DR   EMBL; L43967; AAC71404.1; -; Genomic_DNA.
DR   EMBL; U34967; AAA88885.1; -; Genomic_DNA.
DR   PIR; E64220; E64220.
DR   RefSeq; WP_009885871.1; NZ_AAGX01000007.1.
DR   AlphaFoldDB; P47431; -.
DR   STRING; 243273.MG_185; -.
DR   EnsemblBacteria; AAC71404; AAC71404; MG_185.
DR   KEGG; mge:MG_185; -.
DR   eggNOG; COG1653; Bacteria.
DR   HOGENOM; CLU_017227_1_0_14; -.
DR   OMA; STARFPY; -.
DR   OrthoDB; 622838at2; -.
DR   BioCyc; MGEN243273:G1GJ2-209-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR004890; Lipoprotein_10_C.
DR   InterPro; IPR004984; Mycoplasma_lipoprotein_cen_dom.
DR   Pfam; PF03202; Lipoprotein_10; 1.
DR   Pfam; PF03305; Lipoprotein_X; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..701
FT                   /note="Uncharacterized lipoprotein MG185"
FT                   /id="PRO_0000018723"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CONFLICT        525..528
FT                   /note="GKTA -> WQNC (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   701 AA;  77634 MW;  5E0E2A821ED5C006 CRC64;
     MKFKLFFLSS SVLGPIALFT TACSAVYRFD QVDDGKIKLA TVTSASASGS LTTIISKYNS
     QKDPNDYPVE LVSLDSRGSY SNGKKDLQAK LLAKDKNNFY NLTFNYSDVV SILSRSQMEL
     SFDTVDTSNF DPSFLSFNNN ISNVNPNSIY ALPATVSGEV LVLNGPVLHY ILSSAKKDSN
     TTLSTHSASN NSNKGTMVVA SDSETSSLWT KLEAAAKMNA QTNETQVLKS NSSESNQTQA
     SDTEIKKIWG DYQEVDGGLK NYTFKASVFN NWKDLNDFAT RIAKSFTKLQ TTTKKGEEVQ
     AVFGIGSLEN ALYTALFASG KADYNNFLFN IKNQRINFSN FFNKSSTAFQ NLKTIFNSFK
     SLIDQNGLIS NAHFNTPVND YAKFNQLAFY TSSTARFPYS FASDSVKRLI VNDKTIENKN
     NKSVFEVNLS SDSDNNSNLI GTVSLENSKQ VSLYEKQVDS NKQIGVDALL IKDETLINHL
     KSLKSQVSAK SASETSQTKQ NKTFLAFTTV NADQKAIFDV GKLNGKTAKI IINATETTNA
     KISTLQEKEA IVLKAPQRFE STDPFPIALV QGPSLIGIHA NEREDIETKK FVNWYLNTKV
     QWEENSIKTP AEYVADKASY LLPFKNRLNN TNSYNEFVKT AVSQFADKNV TKFAEPADFL
     SNKVRDGVKS NLNAAINNHS IDFDSFINDL TDYLGSDVKN I