ID   Y1862_STRP1             Reviewed;          99 AA.
AC   P67268; Q48WS7; Q99Y56;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Nucleoid-associated protein SPy_1862/M5005_Spy1580 {ECO:0000255|HAMAP-Rule:MF_00274};
GN   OrderedLocusNames=SPy_1862, M5005_Spy1580;
OS   Streptococcus pyogenes serotype M1.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=301447;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX   PubMed=11296296; DOI=10.1073/pnas.071559398;
RA   Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA   Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA   Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA   Clifton S.W., Roe B.A., McLaughlin R.E.;
RT   "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX   PubMed=16088826; DOI=10.1086/432514;
RA   Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA   Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P.,
RA   Musser J.M.;
RT   "Evolutionary origin and emergence of a highly successful clone of serotype
RT   M1 group A Streptococcus involved multiple horizontal gene transfer
RT   events.";
RL   J. Infect. Dis. 192:771-782(2005).
CC   -!- FUNCTION: Binds to DNA and alters its conformation. May be involved in
CC       regulation of gene expression, nucleoid organization and DNA
CC       protection. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00274}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_00274}.
CC   -!- SIMILARITY: Belongs to the YbaB/EbfC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00274}.
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DR   EMBL; AE004092; AAK34576.1; -; Genomic_DNA.
DR   EMBL; CP000017; AAZ52198.1; -; Genomic_DNA.
DR   RefSeq; NP_269855.1; NC_002737.2.
DR   AlphaFoldDB; P67268; -.
DR   SMR; P67268; -.
DR   STRING; 1314.HKU360_01701; -.
DR   PaxDb; P67268; -.
DR   EnsemblBacteria; AAK34576; AAK34576; SPy_1862.
DR   KEGG; spy:SPy_1862; -.
DR   KEGG; spz:M5005_Spy1580; -.
DR   PATRIC; fig|160490.10.peg.1614; -.
DR   HOGENOM; CLU_140930_1_1_9; -.
DR   OMA; MGNMMKQ; -.
DR   Proteomes; UP000000750; Chromosome.
DR   GO; GO:0043590; C:bacterial nucleoid; IEA:UniProtKB-UniRule.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.1310.10; -; 1.
DR   HAMAP; MF_00274; DNA_YbaB_EbfC; 1.
DR   InterPro; IPR036894; YbaB-like_sf.
DR   InterPro; IPR004401; YbaB/EbfC.
DR   PANTHER; PTHR33449; PTHR33449; 1.
DR   Pfam; PF02575; YbaB_DNA_bd; 1.
DR   PIRSF; PIRSF004555; UCP004555; 1.
DR   SUPFAM; SSF82607; SSF82607; 1.
DR   TIGRFAMs; TIGR00103; DNA_YbaB_EbfC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome.
FT   CHAIN           1..99
FT                   /note="Nucleoid-associated protein SPy_1862/M5005_Spy1580"
FT                   /id="PRO_0000170450"
SQ   SEQUENCE   99 AA;  10976 MW;  FF19FA5714DA8967 CRC64;
     MMNMQNMMKQ AQKLQKQMEQ KQADLAAMQF TGKSAQDLVT ATFTGDKKLV GIDFKEAVVD
     PEDVETLQDM TTQAINDALT QIDETTKKTL GAFAGKLPF