ID   Y186_MYCGE              Reviewed;         250 AA.
AC   P47432;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Uncharacterized lipoprotein MG186;
DE   Flags: Precursor;
GN   OrderedLocusNames=MG186;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
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DR   EMBL; L43967; AAC71405.1; -; Genomic_DNA.
DR   PIR; F64220; F64220.
DR   RefSeq; WP_010869364.1; NC_000908.2.
DR   AlphaFoldDB; P47432; -.
DR   SMR; P47432; -.
DR   STRING; 243273.MG_186; -.
DR   EnsemblBacteria; AAC71405; AAC71405; MG_186.
DR   KEGG; mge:MG_186; -.
DR   eggNOG; COG1525; Bacteria.
DR   HOGENOM; CLU_972608_0_0_14; -.
DR   OMA; NAKINIW; -.
DR   OrthoDB; 1775786at2; -.
DR   BioCyc; MGEN243273:G1GJ2-214-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 2.40.50.90; -; 1.
DR   InterPro; IPR035437; SNase_OB-fold_sf.
DR   InterPro; IPR016071; Staphylococal_nuclease_OB-fold.
DR   InterPro; IPR002071; Thermonucl_AS.
DR   SMART; SM00318; SNc; 1.
DR   SUPFAM; SSF50199; SSF50199; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR   PROSITE; PS01123; TNASE_1; 1.
DR   PROSITE; PS50830; TNASE_3; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Endonuclease; Hydrolase; Lipoprotein; Membrane; Nuclease;
KW   Palmitate; Reference proteome; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           25..250
FT                   /note="Uncharacterized lipoprotein MG186"
FT                   /id="PRO_0000034398"
FT   DOMAIN          44..200
FT                   /note="TNase-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00272"
FT   LIPID           25
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           25
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   250 AA;  28288 MW;  E3C00A92D99650D9 CRC64;
     MKGFLKPNFS LGALFLTLSP IATACIAEKP VNNRFNFNSE QLARLRKARV NHWRDGDTLE
     VSFANNHQKP IRIYAIDTPE KAVLSIQRKS EIELKEANKA TEFAKSLIPI GSEVWIWPLN
     SYSYDREVAA VFFKTNPLQL HFESFAVEMV ANGHALPIAG NDFDFVFSDL DPFNPLKIVG
     IELANGLNNA FNNRKNIFSY LENSFQSITM VYQQRGVDQS WTRYLAPSND FSSTKLGLGL
     TIYELKLNNG