ID   Y186_STAES              Reviewed;         261 AA.
AC   Q8CTZ0; Q8CTY9;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 2.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Uncharacterized lipoprotein SE_0186/SE_0187;
DE   Flags: Precursor;
GN   OrderedLocusNames=SE_0186/SE_0187;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the staphylococcal tandem lipoprotein family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAO03783.1; Type=Frameshift; Note=Produces two separate ORFs.; Evidence={ECO:0000305};
CC       Sequence=AAO03784.1; Type=Frameshift; Note=Produces two separate ORFs.; Evidence={ECO:0000305};
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DR   EMBL; AE015929; AAO03783.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AE015929; AAO03784.1; ALT_FRAME; Genomic_DNA.
DR   RefSeq; NP_763741.1; NC_004461.1.
DR   RefSeq; NP_763742.1; NC_004461.1.
DR   AlphaFoldDB; Q8CTZ0; -.
DR   SMR; Q8CTZ0; -.
DR   STRING; 176280.SE_0186; -.
DR   PRIDE; Q8CTZ0; -.
DR   EnsemblBacteria; AAO03783; AAO03783; SE_0186.
DR   EnsemblBacteria; AAO03784; AAO03784; SE_0187.
DR   KEGG; sep:SE_0186; -.
DR   KEGG; sep:SE_0187; -.
DR   PATRIC; fig|176280.10.peg.169; -.
DR   HOGENOM; CLU_071589_2_1_9; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.50.20.40; -; 1.
DR   InterPro; IPR007595; Csa.
DR   InterPro; IPR038641; Csa_sf.
DR   Pfam; PF04507; DUF576; 1.
DR   TIGRFAMs; TIGR01742; SA_tandem_lipo; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..261
FT                   /note="Uncharacterized lipoprotein SE_0186/SE_0187"
FT                   /id="PRO_0000282195"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   261 AA;  30481 MW;  0014119309C494BA CRC64;
     MKYYGKCISY ISILILTFFI GGCGFMNKEN NKEAEIKESF HKTLSMYPIK NLEDLYDKEG
     YRDEEFEKRD KGTWIINSVM NIQKKGQAME SRGMVLYMNR NTRKTTGHFY TSITTEDKKG
     RVYNKEKNTL FNLKNNKIEP TKPIVDETLK NEIKNFQFFS QYGNFKNLKD YKNGNVSYNP
     NVPSYSAEYQ LSNEDDNVKQ LRKKYDIPTK KAPKLILKGD GDLKGSSIGH KHVELSFVRN
     KEESIYFSDS VEFNPSEVNN E