ID   Y1870_STAA3             Reviewed;         328 AA.
AC   Q2FFK6;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=UPF0421 protein SAUSA300_1870;
GN   OrderedLocusNames=SAUSA300_1870;
OS   Staphylococcus aureus (strain USA300).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=367830;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USA300;
RX   PubMed=16517273; DOI=10.1016/s0140-6736(06)68231-7;
RA   Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA   Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA   Perdreau-Remington F.;
RT   "Complete genome sequence of USA300, an epidemic clone of community-
RT   acquired meticillin-resistant Staphylococcus aureus.";
RL   Lancet 367:731-739(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0421 family. {ECO:0000305}.
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DR   EMBL; CP000255; ABD21306.1; -; Genomic_DNA.
DR   RefSeq; WP_000999713.1; NZ_CP027476.1.
DR   AlphaFoldDB; Q2FFK6; -.
DR   SMR; Q2FFK6; -.
DR   PRIDE; Q2FFK6; -.
DR   EnsemblBacteria; ABD21306; ABD21306; SAUSA300_1870.
DR   KEGG; saa:SAUSA300_1870; -.
DR   HOGENOM; CLU_067028_0_0_9; -.
DR   OMA; ANVMEEW; -.
DR   Proteomes; UP000001939; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010343; ArAE_1.
DR   Pfam; PF06081; ArAE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..328
FT                   /note="UPF0421 protein SAUSA300_1870"
FT                   /id="PRO_0000283013"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   328 AA;  37436 MW;  3AA90C796DF97494 CRC64;
     MNDQWYKHLI GARTIKTGIA IFLTAVFCMA LDLTPIYAIL TAVVTIEPTA KASLIKGYRR
     LPATVIGAGF AVLFTYLFGD QSPFTYALSA TFTILFCTKL KLQVGTNVAV LTSLAMIPGI
     HDAYIFNFLS RTLTAIIGLV TSGLINFMVF PPKYYGQVEE KLSKTDALMY KLFYNRCQEL
     ILSRLQSDKS EKAYKNIFNL NNQVETLISY QRDELSYHKK KECDWKLLNQ LTKRAYTNRL
     FITHLSNIIY LPKNTRVNFS GDEKMALLKI SSSIKDIFYD GSFKREDDSV ETLRSTIKAL
     EISGENQIKS HILYEVLMIY RLLDSRYA