ID   Y1889_STAAM             Reviewed;         328 AA.
AC   Q7A2R3;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=UPF0421 protein SAV1889;
GN   OrderedLocusNames=SAV1889;
OS   Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu50 / ATCC 700699;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0421 family. {ECO:0000305}.
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DR   EMBL; BA000017; BAB58051.1; -; Genomic_DNA.
DR   RefSeq; WP_000999717.1; NC_002758.2.
DR   AlphaFoldDB; Q7A2R3; -.
DR   SMR; Q7A2R3; -.
DR   PaxDb; Q7A2R3; -.
DR   EnsemblBacteria; BAB58051; BAB58051; SAV1889.
DR   KEGG; sav:SAV1889; -.
DR   HOGENOM; CLU_067028_0_0_9; -.
DR   OMA; ANVMEEW; -.
DR   PhylomeDB; Q7A2R3; -.
DR   BioCyc; SAUR158878:SAV_RS10340-MON; -.
DR   Proteomes; UP000002481; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010343; ArAE_1.
DR   Pfam; PF06081; ArAE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..328
FT                   /note="UPF0421 protein SAV1889"
FT                   /id="PRO_0000283017"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   328 AA;  37450 MW;  9AAC5C796DF97222 CRC64;
     MNDQWYKHLI GARTIKTGIA IFLTAVFCMA LDLTPIYAIL TAVVTIEPTA KASLIKGYRR
     LPATVIGAGF AVLFTYLFGD QSPFTYALSA TFTILFCTKL KLQVGTNVAV LTSLAMIPGI
     HDAYIFNFLS RTLTAIIGLV TSGLINFMVF PPKYYGQVEE KLSKTDALMY KLFYNRCQEL
     ILSRLQSDKS EKAYKNIFNL NNQVETLISY QRDELSYHKK KECDWKLLNQ LTKRAYTNRL
     FITHLSNIIY LPKNTRVNFS GDEKMALLKI SSSIKDIFYD GTFKREDDSV ETLRSTIKAL
     EISGENQIKS HILYEVLMIY RLLDSRYA