ID   Y188_MYCGE              Reviewed;         329 AA.
AC   P47434;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Probable ABC transporter permease protein MG188;
GN   OrderedLocusNames=MG188;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
CC   -!- FUNCTION: Probably part of a binding-protein-dependent transport
CC       system. Probably responsible for the translocation of the substrate
CC       across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. MalFG subfamily. {ECO:0000305}.
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DR   EMBL; L43967; AAC71407.1; -; Genomic_DNA.
DR   PIR; H64220; H64220.
DR   RefSeq; WP_009886002.1; NZ_AAGX01000020.1.
DR   AlphaFoldDB; P47434; -.
DR   SMR; P47434; -.
DR   STRING; 243273.MG_188; -.
DR   EnsemblBacteria; AAC71407; AAC71407; MG_188.
DR   KEGG; mge:MG_188; -.
DR   eggNOG; COG1175; Bacteria.
DR   HOGENOM; CLU_016047_0_2_14; -.
DR   OMA; LWYSVQS; -.
DR   OrthoDB; 1688736at2; -.
DR   BioCyc; MGEN243273:G1GJ2-216-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..329
FT                   /note="Probable ABC transporter permease protein MG188"
FT                   /id="PRO_0000060285"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        128..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          88..303
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   329 AA;  37201 MW;  45BFB75ACE8BAE25 CRC64;
     MFKWLLKHHN QPHSLQLGLL DQPLPFWKPF LLFLPALLTT ILFTIIPFFL SLQKGFSANS
     DLYDLSSQSF SLRTFQDLFS ESNFVLGLRN SFLYSLISLP FSIIIAIVIA SAIVFVYKKL
     LRGFWQTVFF LPYVTSGVAI SIAFVYIFDS ASGILNTVFN VNTKWLDSGS RDTFNALWAI
     LIFGVWKNLA FNVLIISTAM LSVNPQLYKV ASLDSANPVR QFFKITLPSI RPTLIFLTTL
     LILGGMQVFP LALFENKPEE AVANGGNSIL LYIFQQIQSG NTNLAGAATL VLFVLGVCYG
     LVLRNGFYLI EWLQWKIKQL YVQKQLTLY