ID   Y189_HELPY              Reviewed;         177 AA.
AC   O24989;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=UPF0114 protein HP_0189;
GN   OrderedLocusNames=HP_0189;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0114 family. {ECO:0000305}.
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DR   EMBL; AE000511; AAD07256.1; -; Genomic_DNA.
DR   PIR; E64543; E64543.
DR   RefSeq; NP_206988.1; NC_000915.1.
DR   RefSeq; WP_000890458.1; NC_018939.1.
DR   AlphaFoldDB; O24989; -.
DR   DIP; DIP-3137N; -.
DR   IntAct; O24989; 1.
DR   MINT; O24989; -.
DR   STRING; 85962.C694_00940; -.
DR   PaxDb; O24989; -.
DR   EnsemblBacteria; AAD07256; AAD07256; HP_0189.
DR   KEGG; hpy:HP_0189; -.
DR   PATRIC; fig|85962.47.peg.204; -.
DR   eggNOG; COG2862; Bacteria.
DR   OMA; HTIMWQV; -.
DR   PhylomeDB; O24989; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   HAMAP; MF_00143; UPF0114; 1.
DR   InterPro; IPR005134; UPF0114.
DR   InterPro; IPR020761; UPF0114_bac.
DR   PANTHER; PTHR38596; PTHR38596; 1.
DR   Pfam; PF03350; UPF0114; 1.
DR   TIGRFAMs; TIGR00645; HI0507; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..177
FT                   /note="UPF0114 protein HP_0189"
FT                   /id="PRO_0000214371"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        145..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   177 AA;  19828 MW;  782125BD0BA303DD CRC64;
     MLEKLIERVL FATRWLLAPL CIAMSLVLVV LGYVFMKELW HMLSHLNTIS ETDLVLSALG
     LVDLLFMAGL VLMVLLASYE SFVSKLDKVD ASEITWLKHT DFNALKLKVS LSIVAISAIF
     LLKRYMSLED VLSSIPKDTP LSHNPIFWQV VIHLVFVCSA LLAAVTNNIA FSQNKAH