ID   Y189_METAR              Reviewed;         599 AA.
AC   Q0W0L6;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=UPF0313 protein UNCMA_01890 {ECO:0000255|HAMAP-Rule:MF_01251};
GN   OrderedLocusNames=UNCMA_01890; ORFNames=RRC361;
OS   Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanocellales; Methanocellaceae; Methanocella.
OX   NCBI_TaxID=351160;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22066 / NBRC 105507 / MRE50;
RX   PubMed=16857943; DOI=10.1126/science.1127062;
RA   Erkel C., Kube M., Reinhardt R., Liesack W.;
RT   "Genome of rice cluster I archaea -- the key methane producers in the rice
RT   rhizosphere.";
RL   Science 313:370-372(2006).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01251};
CC       Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3
CC       cysteines and an exchangeable S-adenosyl-L-methionine.
CC       {ECO:0000255|HAMAP-Rule:MF_01251};
CC   -!- SIMILARITY: Belongs to the UPF0313 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01251}.
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DR   EMBL; AM114193; CAJ38077.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q0W0L6; -.
DR   PRIDE; Q0W0L6; -.
DR   EnsemblBacteria; CAJ38077; CAJ38077; RRC361.
DR   KEGG; rci:RRC361; -.
DR   eggNOG; arCOG04984; Archaea.
DR   OMA; TCMYYTG; -.
DR   Proteomes; UP000000663; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.80.30.20; -; 1.
DR   HAMAP; MF_01251; UPF0313; 1.
DR   InterPro; IPR006638; Elp3/MiaB/NifB.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR023404; rSAM_horseshoe.
DR   InterPro; IPR022946; UPF0313.
DR   InterPro; IPR024560; UPF0313_C.
DR   InterPro; IPR013704; UPF0313_N.
DR   PANTHER; PTHR32331; PTHR32331; 1.
DR   Pfam; PF11842; DUF3362; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   Pfam; PF08497; Radical_SAM_N; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SFLD; SFLDG01069; UPF0313; 1.
DR   SMART; SM00729; Elp3; 1.
DR   TIGRFAMs; TIGR03904; SAM_YgiQ; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome;
KW   S-adenosyl-L-methionine.
FT   CHAIN           1..599
FT                   /note="UPF0313 protein UNCMA_01890"
FT                   /id="PRO_1000067197"
FT   DOMAIN          281..557
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         299
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT   BINDING         303
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT   BINDING         306
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
SQ   SEQUENCE   599 AA;  68047 MW;  745AFDC250FFCC4E CRC64;
     MTKDELKALG WDRCDVVIVS GDAYVDHPSF GVAIIGRVLE KAGFRVGIIA QPDVTDKTSF
     SRLGEPRLCF CVTSGNVDSM VNNYTANKRL RSDDDYSPGN RPHMRPDRAV TVYCNKIRET
     YKTIPIITGG LEASLRRFAH YDYWDDKVRQ SILADAPADM IVYGMGEKTI VDVVGRLKNG
     ERIADITDIR GTTYKTRKIG DLSDFIELPD FKAVSTDKRA FAEAFKTFYD EQDPYYGHTL
     VQRHPKTIIV QNPPALPLTT AEMDAIYDLP YTRYPHPSYK EDIPALRTVR FSITSHRGCF
     GGCAFCAITA HQGRMIQSRS QESILREIRA LTKLPEFKGT ISDIGGPTAD MYMLGCSKRS
     TQGMCRDKLC LYPEPCPNLN KDHSRLITLL NEVRKVPGVK NVFIGSGIRY DLAMQDEQYL
     YHICRQNVSG QLKVAPEHVS RNVTDAMCKP SIEAYDKFVS KYREINKELG KEQYIIPYFI
     SAHPGCTLKD AIQLAEYVRD MGYYVEQVQD FTPTPSTLST CMYYTGYNPY TGQEVYVPKS
     VEERRMYRAL LQYKNPENYD LVKKALISAN RKDLIGYGQN CLIKPVRPAI YKKPGRRKP