ID   Y1918_MYCSJ             Reviewed;         283 AA.
AC   A3PXS9;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Uncharacterized oxidoreductase Mjls_1918;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=Mjls_1918;
OS   Mycobacterium sp. (strain JLS).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; unclassified Mycobacterium.
OX   NCBI_TaxID=164757;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JLS;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Miller C.D., Anderson A.J.,
RA   Sims R.C., Richardson P.;
RT   "Complete sequence of Mycobacterium sp. JLS.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldo/keto reductase family. {ECO:0000305}.
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DR   EMBL; CP000580; ABN97706.1; -; Genomic_DNA.
DR   AlphaFoldDB; A3PXS9; -.
DR   SMR; A3PXS9; -.
DR   STRING; 164757.Mjls_1918; -.
DR   KEGG; mjl:Mjls_1918; -.
DR   HOGENOM; CLU_023205_0_1_11; -.
DR   OMA; KLWPTDQ; -.
DR   BioCyc; MSP164757:G1G8C-1938-MON; -.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.100; -; 1.
DR   InterPro; IPR020471; AKR.
DR   InterPro; IPR018170; Aldo/ket_reductase_CS.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR43827; PTHR43827; 1.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   PIRSF; PIRSF000097; AKR; 1.
DR   PRINTS; PR00069; ALDKETRDTASE.
DR   SUPFAM; SSF51430; SSF51430; 1.
DR   PROSITE; PS00798; ALDOKETO_REDUCTASE_1; 1.
DR   PROSITE; PS00062; ALDOKETO_REDUCTASE_2; 1.
DR   PROSITE; PS00063; ALDOKETO_REDUCTASE_3; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..283
FT                   /note="Uncharacterized oxidoreductase Mjls_1918"
FT                   /id="PRO_0000380742"
FT   ACT_SITE        58
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250"
FT   BINDING         116
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         196..248
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   283 AA;  30187 MW;  6AD98BBF8D19B7CF CRC64;
     MTSTRGEAAG IPSVSLNDGH SIPVLGLGVG ELSESEAERS VAAALEAGYR LIDTAAVYGN
     EAAVGRAVNA SGIPREEIYV TTKLAVADQG FGTSQDAARA SLERLGLDYV DLYLIHWPAG
     DHGKYIDSWG GLMKAKQDGV ARSIGVCNFN AEHLSNIIDL SFFTPAINQI ELHPLLNQAE
     LREVNAGYGI VTEAYGPLGV GRLLDHAAVT GVAQAHDKTP AQVLLRWSIQ LGNVVIARSA
     NPDRITSNLE VFDFELTDDE MATLNGLDEG TRFRPDPETY TGP