ID   Y191_CLOAB              Reviewed;         283 AA.
AC   Q97MK5;
DT   27-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator CA_C0191;
GN   OrderedLocusNames=CA_C0191;
OS   Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710
OS   / VKM B-1787).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=272562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787;
RX   PubMed=11466286; DOI=10.1128/jb.183.16.4823-4838.2001;
RA   Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R.,
RA   Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F.,
RA   Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V.,
RA   Smith D.R.;
RT   "Genome sequence and comparative analysis of the solvent-producing
RT   bacterium Clostridium acetobutylicum.";
RL   J. Bacteriol. 183:4823-4838(2001).
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DR   EMBL; AE001437; AAK78173.1; -; Genomic_DNA.
DR   PIR; B96923; B96923.
DR   RefSeq; NP_346833.1; NC_003030.1.
DR   RefSeq; WP_010963515.1; NC_003030.1.
DR   AlphaFoldDB; Q97MK5; -.
DR   SMR; Q97MK5; -.
DR   STRING; 272562.CA_C0191; -.
DR   EnsemblBacteria; AAK78173; AAK78173; CA_C0191.
DR   GeneID; 44996683; -.
DR   KEGG; cac:CA_C0191; -.
DR   PATRIC; fig|272562.8.peg.377; -.
DR   eggNOG; COG1737; Bacteria.
DR   HOGENOM; CLU_055769_0_0_9; -.
DR   OMA; QDLEHAP; -.
DR   OrthoDB; 992687at2; -.
DR   Proteomes; UP000000814; Chromosome.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   CDD; cd05013; SIS_RpiR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR000281; HTH_RpiR.
DR   InterPro; IPR035472; RpiR-like_SIS.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF01418; HTH_6; 1.
DR   Pfam; PF01380; SIS; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF53697; SSF53697; 1.
DR   PROSITE; PS51071; HTH_RPIR; 1.
DR   PROSITE; PS51464; SIS; 1.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..283
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   CA_C0191"
FT                   /id="PRO_0000068630"
FT   DOMAIN          2..78
FT                   /note="HTH rpiR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00390"
FT   DOMAIN          124..264
FT                   /note="SIS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00797"
FT   DNA_BIND        38..57
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00390"
SQ   SEQUENCE   283 AA;  31672 MW;  136727BB57935C5D CRC64;
     MYGSLIRIKE IINDLNPSER KIAEYILNNS KAISDLSIKE LAGKSGSSKS AVVRLCKILN
     YKGYKEFRIA IAKDTVNVDK EENRYTDINP KDDLHTIIKN ISYNNKKSID NTMEVLSEEL
     VEKASEAISK AYRVDFYGIG ASYIVAMDAF QKFMRINKNV RATPDTHLQV EFASNLKKGD
     VAVAISYTGE TKDTFESIKA AKEAGATTIS VTKFGSNSIS DLCDINLFVL SPEITFRSGA
     MSSRIAQLNV IDILFTSVAG RMFEEVKEFL ENTRKSTRVK RIK