ID   Y191_METTH              Reviewed;         305 AA.
AC   O26293;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Putative glutamine amidotransferase MTH_191;
DE            EC=2.4.2.-;
GN   OrderedLocusNames=MTH_191;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
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DR   EMBL; AE000666; AAB84697.1; -; Genomic_DNA.
DR   PIR; A69122; A69122.
DR   RefSeq; WP_010875830.1; NC_000916.1.
DR   AlphaFoldDB; O26293; -.
DR   SMR; O26293; -.
DR   STRING; 187420.MTH_191; -.
DR   PRIDE; O26293; -.
DR   EnsemblBacteria; AAB84697; AAB84697; MTH_191.
DR   GeneID; 1470152; -.
DR   KEGG; mth:MTH_191; -.
DR   PATRIC; fig|187420.15.peg.162; -.
DR   HOGENOM; CLU_077077_0_0_2; -.
DR   OMA; FKGVGFP; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.20.10; -; 2.
DR   InterPro; IPR017932; GATase_2_dom.
DR   InterPro; IPR029055; Ntn_hydrolases_N.
DR   SUPFAM; SSF56235; SSF56235; 1.
DR   PROSITE; PS51278; GATASE_TYPE_2; 1.
PE   3: Inferred from homology;
KW   Glutamine amidotransferase; Reference proteome; Transferase.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..305
FT                   /note="Putative glutamine amidotransferase MTH_191"
FT                   /id="PRO_0000056942"
FT   DOMAIN          2..305
FT                   /note="Glutamine amidotransferase type-2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00609"
FT   ACT_SITE        2
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   305 AA;  33910 MW;  56CD141A9D164A66 CRC64;
     MCGIAGVVYK DGKLHSVGAD MTRMLHALQH RGPDSAGFAI YGGLGLEEND YLLNIEVKDK
     PGLLDMVKET VELVSPIGSD EVIPSVENHI IYRCRITLES FSQLKPLIMD IDSIDDVIVL
     NGSHSFEMIK DVGSVLEIAD RYDTWSKKGT HAIGHTRFST ESIVDRYHAH PFQSYIIPDI
     TVVHNGQITN YWKIREPLER KGHIFETNND TECIVHYVAD KLASGYSLEE ALEQSVKDMD
     GPFSYIVGTP QGVGIAKDQL GLRPGVMAEN DEVFAVASEE VSLREVMDTS EVEQISPGEV
     RVYEI