ID   Y191_SYNY3              Reviewed;         303 AA.
AC   P22039; Q55706;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=Uncharacterized PKHD-type hydroxylase sll0191;
DE            EC=1.14.11.-;
DE   AltName: Full=ORF60-3;
GN   OrderedLocusNames=sll0191;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27184 / PCC 6803 / N-1;
RX   PubMed=8590279; DOI=10.1093/dnares/2.4.153;
RA   Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N.,
RA   Sugiura M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb region
RT   from map positions 64% to 92% of the genome.";
RL   DNA Res. 2:153-166(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1670771; DOI=10.1016/s0021-9258(18)52401-7;
RA   Chitnis P.R., Nelson N.;
RT   "Molecular cloning of the genes encoding two chaperone proteins of the
RT   cyanobacterium Synechocystis sp. PCC 6803.";
RL   J. Biol. Chem. 266:58-65(1991).
CC   -!- COFACTOR:
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU00805};
CC       Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000255|PROSITE-
CC       ProRule:PRU00805};
CC   -!- COFACTOR:
CC       Name=L-ascorbate; Xref=ChEBI:CHEBI:38290; Evidence={ECO:0000250};
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DR   EMBL; BA000022; BAA10239.1; -; Genomic_DNA.
DR   EMBL; M57517; AAA27285.1; -; Genomic_DNA.
DR   PIR; S76387; S76387.
DR   AlphaFoldDB; P22039; -.
DR   SMR; P22039; -.
DR   IntAct; P22039; 3.
DR   STRING; 1148.1001611; -.
DR   PaxDb; P22039; -.
DR   EnsemblBacteria; BAA10239; BAA10239; BAA10239.
DR   KEGG; syn:sll0191; -.
DR   eggNOG; COG3751; Bacteria.
DR   OMA; TAHNDGC; -.
DR   PhylomeDB; P22039; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   InterPro; IPR005123; Oxoglu/Fe-dep_dioxygenase.
DR   InterPro; IPR006620; Pro_4_hyd_alph.
DR   InterPro; IPR044862; Pro_4_hyd_alph_FE2OG_OXY.
DR   Pfam; PF13640; 2OG-FeII_Oxy_3; 1.
DR   SMART; SM00702; P4Hc; 1.
DR   PROSITE; PS51471; FE2OG_OXY; 1.
PE   3: Inferred from homology;
KW   Dioxygenase; Iron; Metal-binding; Oxidoreductase; Reference proteome;
KW   Vitamin C.
FT   CHAIN           1..303
FT                   /note="Uncharacterized PKHD-type hydroxylase sll0191"
FT                   /id="PRO_0000206689"
FT   DOMAIN          173..300
FT                   /note="Fe2OG dioxygenase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00805"
FT   CONFLICT        216
FT                   /note="A -> S (in Ref. 3; AAA27285)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        245..303
FT                   /note="LKNNTITTHPKFQTITPINNSIIFFNSRCRHEVMSVVCPSREFAHSRFTVNG
FT                   WIRKKMN -> A (in Ref. 3; AAA27285)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   303 AA;  34819 MW;  0B91B8587842F037 CRC64;
     MNRGAKVKTN GDNLALSTRA KKLLTKSIDT LETIIDNDQC SPQEKATIAL KILEMAGIFT
     EFKHHSVDKL VAKAEEKIRR LQSQYPQINL SLSEPTLHQQ SESIFLPGTY GEIKNFLSPE
     ENQKIITEAI DKKEEYIKSN TTTKANQYRQ SYVLFSQKIP ALSALIRERI KQKLPELLGQ
     LNFSPFEVAE IELQLTAHND GCYYRIHNDA GSEKTASRQI TYVYYFYQEP KAFSGGELRL
     YDTELKNNTI TTHPKFQTIT PINNSIIFFN SRCRHEVMSV VCPSREFAHS RFTVNGWIRK
     KMN