ID   Y1941_BACAN             Reviewed;         147 AA.
AC   Q81RU6; Q6I023; Q6KU02;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 119.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator BA_1941/GBAA_1941/BAS1801;
GN   OrderedLocusNames=BA_1941, GBAA_1941, BAS1801;
OS   Bacillus anthracis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1392;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames / isolate Porton;
RX   PubMed=12721629; DOI=10.1038/nature01586;
RA   Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T.,
RA   Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R.,
RA   Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M.,
RA   Kolonay J.F., Beanan M.J., Dodson R.J., Brinkac L.M., Gwinn M.L.,
RA   DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C.,
RA   Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y.,
RA   Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M.,
RA   Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E.,
RA   White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M.,
RA   Hanna P.C., Kolstoe A.-B., Fraser C.M.;
RT   "The genome sequence of Bacillus anthracis Ames and comparison to closely
RT   related bacteria.";
RL   Nature 423:81-86(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames ancestor;
RX   PubMed=18952800; DOI=10.1128/jb.01347-08;
RA   Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D.,
RA   Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.;
RT   "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'.";
RL   J. Bacteriol. 191:445-446(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sterne;
RA   Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K.,
RA   Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R.,
RA   Richardson P., Rubin E., Tice H.;
RT   "Complete genome sequence of Bacillus anthracis Sterne.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   INDUCTION, AND MUTANT STUDIES.
RC   STRAIN=Sterne;
RX   PubMed=17470545; DOI=10.1128/iai.01345-06;
RA   Bergman N.H., Anderson E.C., Swenson E.E., Janes B.K., Fisher N.,
RA   Niemeyer M.M., Miyoshi A.D., Hanna P.C.;
RT   "Transcriptional profiling of Bacillus anthracis during infection of host
RT   macrophages.";
RL   Infect. Immun. 75:3434-3444(2007).
CC   -!- INDUCTION: Up-regulated following infection of host macrophages.
CC       {ECO:0000269|PubMed:17470545}.
CC   -!- MISCELLANEOUS: Deletion results in virulence attenuation.
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DR   EMBL; AE016879; AAP25836.1; -; Genomic_DNA.
DR   EMBL; AE017334; AAT31060.1; -; Genomic_DNA.
DR   EMBL; AE017225; AAT54116.1; -; Genomic_DNA.
DR   RefSeq; NP_844350.1; NC_003997.3.
DR   RefSeq; WP_001205522.1; NZ_WXXJ01000007.1.
DR   RefSeq; YP_028065.1; NC_005945.1.
DR   AlphaFoldDB; Q81RU6; -.
DR   SMR; Q81RU6; -.
DR   STRING; 260799.BAS1801; -.
DR   DNASU; 1086066; -.
DR   EnsemblBacteria; AAP25836; AAP25836; BA_1941.
DR   EnsemblBacteria; AAT31060; AAT31060; GBAA_1941.
DR   GeneID; 45021867; -.
DR   KEGG; ban:BA_1941; -.
DR   KEGG; bar:GBAA_1941; -.
DR   KEGG; bat:BAS1801; -.
DR   PATRIC; fig|198094.11.peg.1913; -.
DR   eggNOG; COG1846; Bacteria.
DR   HOGENOM; CLU_083287_27_2_9; -.
DR   OMA; MMRFTHE; -.
DR   Proteomes; UP000000427; Chromosome.
DR   Proteomes; UP000000594; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR000835; HTH_MarR-typ.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01047; MarR; 1.
DR   PRINTS; PR00598; HTHMARR.
DR   SMART; SM00347; HTH_MARR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50995; HTH_MARR_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..147
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   BA_1941/GBAA_1941/BAS1801"
FT                   /id="PRO_0000293590"
FT   DOMAIN          1..137
FT                   /note="HTH marR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
FT   DNA_BIND        53..76
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00345"
SQ   SEQUENCE   147 AA;  17313 MW;  D66C5A7EF195D83F CRC64;
     MRDNTIGSLI WLRLIRFTNQ SNQMSNEFLK RFDLTTAQFD VLLQIRTYQP LTQMELAEKV
     TVTQGGISRM LTRLEKEGYI VRKQDWKTKT ISLTEQGEAA LERALPEQLA FQSSFFDDVL
     NEEEQKILYE LMTKVHKHSE KKELPKE