ID   CAPSP_ADEB2             Reviewed;         153 AA.
AC   Q96623;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   23-FEB-2022, entry version 51.
DE   RecName: Full=Penton protein;
DE            Short=CP-P;
DE   AltName: Full=Penton base protein;
DE   AltName: Full=Protein III;
DE   Flags: Fragment;
GN   ORFNames=L2;
OS   Bovine adenovirus 2 (BAdV-2) (Mastadenovirus bos2).
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Rowavirales; Adenoviridae; Mastadenovirus; Ovine mastadenovirus A.
OX   NCBI_TaxID=114429;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=11074122; DOI=10.1016/s0168-1702(00)00201-x;
RA   Rusvai M., Harrach B., Banrevi A., Evans P.S., Benko M.;
RT   "Identification and sequence analysis of the core protein genes of bovine
RT   adenovirus 2.";
RL   Virus Res. 70:25-30(2000).
CC   -!- FUNCTION: Major capsid protein that self-associates to form penton base
CC       pentamers, each in the shape of a pentagon, situated at the 12 vertices
CC       of the pseudo T=25 capsid. Involved in virus secondary attachment to
CC       host cell after initial attachment by the fiber protein, and in
CC       endocytosis of virions. As the virus enters the host cell, penton
CC       proteins are shed concomitant with virion acidification in the endosome
CC       (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with the fiber protein (via N-terminal tail region).
CC       Interacts with the capsid vertex protein; this interaction binds the
CC       penton base to neighboring peripentonal hexons (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Host nucleus {ECO:0000250}.
CC       Note=Located at each vertex of the virion. {ECO:0000250}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC   -!- MISCELLANEOUS: All late proteins expressed from the major late promoter
CC       are produced by alternative splicing and alternative polyadenylation of
CC       the same gene giving rise to non-overlapping ORFs. A leader sequence is
CC       present in the N-terminus of all these mRNAs and is recognized by the
CC       viral shutoff protein to provide expression although conventional
CC       translation via ribosome scanning from the cap has been shut off in the
CC       host cell (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the adenoviridae penton family. {ECO:0000305}.
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DR   EMBL; U44123; AAB16755.1; -; Genomic_DNA.
DR   SMR; Q96623; -.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0039623; C:T=25 icosahedral viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0075509; P:endocytosis involved in viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
DR   InterPro; IPR002605; Adeno_Penton_B.
DR   Pfam; PF01686; Adeno_Penton_B; 1.
PE   2: Evidence at transcript level;
KW   Capsid protein; Host nucleus; Host-virus interaction; Late protein;
KW   T=25 icosahedral capsid protein; Viral attachment to host cell;
KW   Viral penetration into host cytoplasm; Virion; Virus endocytosis by host;
KW   Virus entry into host cell.
FT   CHAIN           <1..153
FT                   /note="Penton protein"
FT                   /id="PRO_0000221875"
FT   NON_TER         1
SQ   SEQUENCE   153 AA;  17319 MW;  A8A17859A5A569C6 CRC64;
     IRNATLLVTP DVTCGMEQVY WSIPDMYVEP VTFKASQNVS NYPVIGVELM PQRPRSFYNA
     QAVYSQMIQE NTNQTMVFNR FPDNQIFLRP PESTITSISE NVPTQTDHGT LPIRNSVSGV
     QRVTLTDARR RASPYVYKSI AVAQPKVLSS RTF