ID   Y195_VIBCH              Reviewed;         302 AA.
AC   Q9KVF1;
DT   19-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Uncharacterized transporter VC_0195;
GN   OrderedLocusNames=VC_0195;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
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DR   EMBL; AE003852; AAF93371.1; -; Genomic_DNA.
DR   PIR; D82351; D82351.
DR   RefSeq; NP_229852.1; NC_002505.1.
DR   AlphaFoldDB; Q9KVF1; -.
DR   SMR; Q9KVF1; -.
DR   STRING; 243277.VC_0195; -.
DR   DNASU; 2614559; -.
DR   EnsemblBacteria; AAF93371; AAF93371; VC_0195.
DR   KEGG; vch:VC_0195; -.
DR   PATRIC; fig|243277.26.peg.176; -.
DR   eggNOG; COG2962; Bacteria.
DR   HOGENOM; CLU_054508_1_0_6; -.
DR   OMA; HRMVWSL; -.
DR   BioCyc; VCHO:VC0195-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   InterPro; IPR000620; EamA_dom.
DR   InterPro; IPR004626; RarD.
DR   PANTHER; PTHR22911:SF114; PTHR22911:SF114; 1.
DR   Pfam; PF00892; EamA; 1.
DR   TIGRFAMs; TIGR00688; rarD; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..302
FT                   /note="Uncharacterized transporter VC_0195"
FT                   /id="PRO_0000108161"
FT   TRANSMEM        13..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        77..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        106..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        154..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        217..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        246..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        275..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          22..149
FT                   /note="EamA"
SQ   SEQUENCE   302 AA;  33179 MW;  2C8064A1A40242BC CRC64;
     MFMTPDQQDA KKGILLAISA YTMWGIAPIY FKALGAVSAL EILSHRVVWS FVLLAVLIHL
     GRRWRSVVGV VHTPRKFWLL LVTALLVGGN WLIFIWSINA NHMLDASLGY YINPLLNVLL
     GMLFLGERLR KLQWFAVALA AIGVGIQLVV FGSVPIVAIA LATSFGFYGL LRKKIQVDAQ
     TGLFLETLFM LPAAAIYLIW LADTPTSDMA LNTWQLNLLL VCAGVVTTLP LLCFTGAAAR
     LKLSTLGFFQ YIGPSLMFLL AVLVYGEAFT SDKAITFAFI WSALVIFSVD GLKAGHAARR
     AR