Y1960_ARATH
ID Y1960_ARATH Reviewed; 714 AA.
AC F4I114; O80540;
DT 09-JAN-2013, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 69.
DE RecName: Full=Probable serine/threonine-protein kinase At1g09600;
DE EC=2.7.11.-;
GN OrderedLocusNames=At1g09600; ORFNames=F14J9.26;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC33218.1; Type=Erroneous gene model prediction; Note=The predicted gene At1g09600 has been split into 2 genes: At1g09600 and At1g09610.; Evidence={ECO:0000305};
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DR EMBL; AC003970; AAC33218.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE28467.1; -; Genomic_DNA.
DR PIR; G86229; G86229.
DR RefSeq; NP_172431.1; NM_100832.2.
DR AlphaFoldDB; F4I114; -.
DR SMR; F4I114; -.
DR STRING; 3702.AT1G09600.1; -.
DR iPTMnet; F4I114; -.
DR PaxDb; F4I114; -.
DR PRIDE; F4I114; -.
DR ProteomicsDB; 232378; -.
DR EnsemblPlants; AT1G09600.1; AT1G09600.1; AT1G09600.
DR GeneID; 837487; -.
DR Gramene; AT1G09600.1; AT1G09600.1; AT1G09600.
DR KEGG; ath:AT1G09600; -.
DR Araport; AT1G09600; -.
DR TAIR; locus:2012290; AT1G09600.
DR eggNOG; KOG0600; Eukaryota.
DR HOGENOM; CLU_000288_78_2_1; -.
DR InParanoid; F4I114; -.
DR OMA; SEWAHQF; -.
DR OrthoDB; 925637at2759; -.
DR PRO; PR:F4I114; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4I114; baseline and differential.
DR Genevisible; F4I114; AT.
DR GO; GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004693; F:cyclin-dependent protein serine/threonine kinase activity; IBA:GO_Central.
DR GO; GO:0008353; F:RNA polymerase II CTD heptapeptide repeat kinase activity; IBA:GO_Central.
DR GO; GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; IBA:GO_Central.
DR GO; GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IBA:GO_Central.
DR GO; GO:0006468; P:protein phosphorylation; IBA:GO_Central.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; SSF56112; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding; Kinase; Lipoprotein; Myristate; Nucleotide-binding;
KW Reference proteome; Serine/threonine-protein kinase; Transferase.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000255"
FT CHAIN 2..714
FT /note="Probable serine/threonine-protein kinase At1g09600"
FT /id="PRO_0000420836"
FT DOMAIN 163..447
FT /note="Protein kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 471..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..47
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 471..493
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..531
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..570
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 287
FT /note="Proton acceptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159,
FT ECO:0000255|PROSITE-ProRule:PRU10027"
FT BINDING 169..177
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT BINDING 192
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00159"
FT LIPID 2
FT /note="N-myristoyl glycine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 714 AA; 79698 MW; A6A399B3CFAE7EB9 CRC64;
MGCNCTKGTR PDNDNVDNSN SIVSNVNVKE RRSKPKKTPK KKKKSKSASS SKDNNVGFEE
RSNDNKEASL TLLIPIDAKK DDESEKKVNL ERKSSRLVFQ RRPTGIEVGA NNIGTLQQPK
MTRICSVSNG ERGAQVMAGW PSWLASVAGE AINGWIPRKA DSFEKLEKIG QGTYSSVYKA
RDLETNQLVA LKKVRFANMD PDSVRFMARE IIILRRLDHP NVMKLEGLIT SRVSGSMYLI
FEYMEHDLAG LASTPGINFS EAQIKCYMKQ LLHGLEHCHS RGVLHRDIKG SNLLLDHNNN
LKIGDFGLAN FYQGHQKQPL TSRVVTLWYR PPELLLGSTD YGVTVDLWST GCILAELFTG
KPIMPGRTEV EQLHKIFKLC GSPSEEYWKI SKLPHATIFK PQQPYKRCVA ETFKSLPSSA
LALVEVLLAV EPDARGTTAS ALESEFFTTS PLASDPSSLP KYQPRKEIDV KAQEEEAKRK
KDTSSKQNDS KQVSRESKAV PAPDSNAESL TSIQKRQGQH NQVSNSDKFN PGEDAASFRI
EPLKSGTAKD GHTRYGVSSV NRNGENVMMG SSRSPRKELR TQRSFVQRGT AQLSRFSNSV
AARDGSHFAI ANPRWFEDSY NNNNGRQNGG AWSQRLVVKH KEFTKHKESI TVNGEKKERM
HCSGPLVSAG GNLDEMLKEH ERQIQLAVRK ARVDKKTNRG DNRQTQAFLA ANGR
