ID   Y1964_CLOBH             Reviewed;         430 AA.
AC   A5I389; A7G4P9;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=UPF0597 protein CBO1964/CLC_1909 {ECO:0000255|HAMAP-Rule:MF_01845};
GN   OrderedLocusNames=CBO1964, CLC_1909;
OS   Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=441771;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hall / ATCC 3502 / NCTC 13319 / Type A;
RX   PubMed=17519437; DOI=10.1101/gr.6282807;
RA   Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G.,
RA   Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L.,
RA   Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M.,
RA   Churcher C., Quail M.A., Chillingworth T., Feltwell T., Fraser A.,
RA   Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S.,
RA   Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M.,
RA   White B., Whithead S., Parkhill J.;
RT   "Genome sequence of a proteolytic (Group I) Clostridium botulinum strain
RT   Hall A and comparative analysis of the clostridial genomes.";
RL   Genome Res. 17:1082-1092(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hall / ATCC 3502 / NCTC 13319 / Type A;
RX   PubMed=18060065; DOI=10.1371/journal.pone.0001271;
RA   Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C.,
RA   Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.;
RT   "Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4
RT   and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within
RT   plasmids.";
RL   PLoS ONE 2:E1271-E1271(2007).
CC   -!- SIMILARITY: Belongs to the UPF0597 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01845}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000727; ABS36556.1; -; Genomic_DNA.
DR   EMBL; AM412317; CAL83506.1; -; Genomic_DNA.
DR   RefSeq; WP_011986501.1; NC_009698.1.
DR   RefSeq; YP_001254467.1; NC_009495.1.
DR   RefSeq; YP_001387764.1; NC_009698.1.
DR   AlphaFoldDB; A5I389; -.
DR   GeneID; 5186219; -.
DR   KEGG; cbh:CLC_1909; -.
DR   KEGG; cbo:CBO1964; -.
DR   PATRIC; fig|413999.7.peg.1939; -.
DR   HOGENOM; CLU_051840_0_0_9; -.
DR   OMA; LSGMICD; -.
DR   PRO; PR:A5I389; -.
DR   Proteomes; UP000001986; Chromosome.
DR   GO; GO:0080146; F:L-cysteine desulfhydrase activity; IBA:GO_Central.
DR   GO; GO:0019450; P:L-cysteine catabolic process to pyruvate; IBA:GO_Central.
DR   HAMAP; MF_01845; UPF0597; 1.
DR   InterPro; IPR005130; Ser_deHydtase-like_asu.
DR   InterPro; IPR021144; UPF0597.
DR   PANTHER; PTHR30501; PTHR30501; 1.
DR   Pfam; PF03313; SDH_alpha; 1.
DR   PIRSF; PIRSF006054; UCP006054; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..430
FT                   /note="UPF0597 protein CBO1964/CLC_1909"
FT                   /id="PRO_0000339795"
SQ   SEQUENCE   430 AA;  45994 MW;  98E17DE36647BC63 CRC64;
     MLTKENLLAL LKQEVVPALG CTEPVCVALA TADAYHAIGG RIVSIKIEVN PGIYKNGMSV
     GIPGFDRVGL KYAASLGAVI GNPEKKLELL EDITAEVSQK AIKIVENSQV VVVIKHEEAQ
     LYVRAEIITT AGMGISEIRG THSNIIFTKR NNDMLLQKEY SVDSDDSLHQ QLKLMGIAEI
     RKLIDECKEE ELSFLLDGVD MNERLADYGL EHSLGIGIAS ALQEKMTTDI MGDNLFSRTM
     LRVASSAEGR MSGCPYAVMS SAGSGNHGIT AILPVTEMAR YLNSSREQLV KALAFSHTLN
     VYIKLFTGKL SATCGCGVSA ATAASAAMVW LMGGNEHQIA NAIINMSGNL TGMICDGGKI
     GCALKLATAT NAALMCAYLA MSDVALQPSD GICDVTAEQV IRNMGQVSNP GMVETDQTIL
     SIMIEKDQRK