CAPSP_BPAR1
ID CAPSP_BPAR1 Reviewed; 427 AA.
AC D4Z9X5;
DT 04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT 15-JUN-2010, sequence version 1.
DT 07-OCT-2020, entry version 34.
DE RecName: Full=Capsid vertex protein {ECO:0000250|UniProtKB:P19896, ECO:0000255|HAMAP-Rule:MF_04113};
DE AltName: Full=Gene product 24 {ECO:0000250|UniProtKB:P19896};
DE AltName: Full=gp24 {ECO:0000250|UniProtKB:P19896, ECO:0000255|HAMAP-Rule:MF_04113};
DE Contains:
DE RecName: Full=Mature capsid vertex protein {ECO:0000255|HAMAP-Rule:MF_04113};
DE AltName: Full=gp24* {ECO:0000255|HAMAP-Rule:MF_04113};
GN Name=24 {ECO:0000312|EMBL:BAI83187.1};
GN OrderedLocusNames=AR1_179 {ECO:0000312|EMBL:BAI83187.1};
OS Escherichia phage AR1 (Bacteriophage AR1).
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX NCBI_TaxID=66711;
OH NCBI_TaxID=83334; Escherichia coli O157:H7.
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR1;
RX PubMed=9758911; DOI=10.1007/bf02253447;
RA Yu S.L., Ding H.C., Seah J.N., Wu K.M., Chang Y.C., Chang K.S., Tam M.F.,
RA Syu W.J.;
RT "Characterization of a phage specific to hemorrhagic Escherichia coli
RT O157:H7 and disclosure of variations in host outer membrane protein ompC.";
RL J. Biomed. Sci. 5:370-382(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR1;
RX PubMed=11029414; DOI=10.1128/jb.182.21.5962-5968.2000;
RA Yu S.L., Ko K.L., Chen C.S., Chang Y.C., Syu W.J.;
RT "Characterization of the distal tail fiber locus and determination of the
RT receptor for phage AR1, which specifically infects Escherichia coli
RT O157:H7.";
RL J. Bacteriol. 182:5962-5968(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR1;
RX PubMed=11808783; DOI=10.4315/0362-028x-65.1.12;
RA Chang T.C., Ding H.C., Chen S.W.;
RT "A conductance method for the identification of Escherichia coli O157:H7
RT using bacteriophage AR1.";
RL J. Food Prot. 65:12-17(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR1;
RX PubMed=12542256;
RA Liao C.P., Syu W.J.;
RT "Analysis of the baseplate region of phage AR1 that specifically infects
RT Escherichia coli O157:H7.";
RL J. Microbiol. Immunol. Infect. 35:269-271(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR1;
RX PubMed=12957924; DOI=10.1128/aem.69.9.5364-5371.2003;
RA Goodridge L., Gallaccio A., Griffiths M.W.;
RT "Morphological, host range, and genetic characterization of two
RT coliphages.";
RL Appl. Environ. Microbiol. 69:5364-5371(2003).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AR1;
RX PubMed=21507986; DOI=10.1128/jvi.02378-10;
RA Liao W.-C., Ng W.V., Lin I.-H., Syu W.-J., Liu T.-T., Chang C.-H.;
RT "T4-Like genome organization of the Escherichia coli O157:H7 lytic phage
RT AR1.";
RL J. Virol. 85:6567-6578(2011).
CC -!- FUNCTION: Capsid protein that self-associates to form pentons, building
CC the capsid in association with hexamers of the major capsid protein and
CC one dodecamer of the portal protein. The capsid vertex protein self-
CC associates to form 11 pentons, building the T=13 laevo capsid in
CC association with 160 hexamers of the major capsid protein.
CC {ECO:0000250|UniProtKB:P19896, ECO:0000255|HAMAP-Rule:MF_04113}.
CC -!- SUBUNIT: Homopentamer. Interacts with the portal protein. Interacts
CC with the major capsid protein that forms hexamers. {ECO:0000255|HAMAP-
CC Rule:MF_04113}.
CC -!- SUBCELLULAR LOCATION: [Capsid vertex protein]: Virion. Note=Part of the
CC capsid icosahedric shell of the immature virion. The capsid contains 55
CC copies. {ECO:0000250|UniProtKB:P19896, ECO:0000255|HAMAP-
CC Rule:MF_04113}.
CC -!- SUBCELLULAR LOCATION: [Mature capsid vertex protein]: Virion. Note=Part
CC of the capsid icosahedric shell of the mature virion. The capsid
CC contains 55 copies. {ECO:0000250|UniProtKB:P19896, ECO:0000255|HAMAP-
CC Rule:MF_04113}.
CC -!- PTM: A proteolytic cleavage gives rise to the mature capsid vertex
CC protein. {ECO:0000255|HAMAP-Rule:MF_04113}.
CC -!- SIMILARITY: Belongs to the Tevenvirinae capsid vertex family.
CC {ECO:0000305}.
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DR EMBL; AP011113; BAI83187.1; -; Genomic_DNA.
DR RefSeq; YP_009167990.1; NC_027983.1.
DR SMR; D4Z9X5; -.
DR GeneID; 26041919; -.
DR KEGG; vg:26041919; -.
DR Proteomes; UP000007649; Genome.
DR GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule.
DR HAMAP; MF_04113; CAPSID_P_T4; 1.
DR InterPro; IPR038999; CAPSP.
DR InterPro; IPR010762; Gp23/Gp24_T4-like.
DR Pfam; PF07068; Gp23; 1.
PE 3: Inferred from homology;
KW Capsid protein; Late protein; Virion.
FT CHAIN 1..427
FT /note="Capsid vertex protein"
FT /id="PRO_0000432342"
FT CHAIN 11..427
FT /note="Mature capsid vertex protein"
FT /id="PRO_0000432343"
FT SITE 10..11
FT /note="Cleavage"
FT /evidence="ECO:0000250|UniProtKB:P19896, ECO:0000255|HAMAP-
FT Rule:MF_04113"
SQ SEQUENCE 427 AA; 47007 MW; 26CFB315C9E91C5D CRC64;
MAKINELLRE STTTNSNSIG RPNLVALTRA TTKLIYSDIV ATQRTNQPVA AFYGIKYLNP
DNEFTFKTGA TYAGEAGYVD REQITELTEE SKLTLNKGDL FKYNNIVYKV LEDTPFADIE
ESDLELALQI AIVLLKVRLF SDAASTSKFE SSDSEIADAR FQINKWQTAV KSRKLKTGIT
VELAQDLEAN GFDAPNFLED LLATEMADEI NKDILQSLIT VSKRYKVTGI TDTGFIDLSY
ASAPEAGRSL YRMVCEMVSH IQKESTYTAT FCVASARAAA ILAASGWLKH KPEDDKYLSQ
NAYGFLANGL PLYCDTNSPL DYVIVGVVEN IGEKEIVGSI FYAPYTEGLD LDDPEHVGAF
KVVVDPESLQ PSIGLLVRYA LSANPYTVAK DEKEARVIDG GDMDKMAGRS DLSVLLGVKL
PKIIIDE
