ID   Y1972_SYNY3             Reviewed;         359 AA.
AC   P74117;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Uncharacterized PIN and TRAM-domain containing protein slr1972;
DE   AltName: Full=Putative RNase slr1972;
DE            EC=3.1.-.-;
GN   OrderedLocusNames=slr1972;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: An RNase. {ECO:0000305}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the ycf81 family. {ECO:0000305}.
CC   -!- SIMILARITY: In the central section; belongs to the PINc/VapC protein
CC       family. {ECO:0000305}.
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DR   EMBL; BA000022; BAA18203.1; -; Genomic_DNA.
DR   PIR; S75642; S75642.
DR   AlphaFoldDB; P74117; -.
DR   SMR; P74117; -.
DR   STRING; 1148.1653288; -.
DR   PaxDb; P74117; -.
DR   EnsemblBacteria; BAA18203; BAA18203; BAA18203.
DR   KEGG; syn:slr1972; -.
DR   eggNOG; COG4956; Bacteria.
DR   InParanoid; P74117; -.
DR   OMA; TMPTDLL; -.
DR   PhylomeDB; P74117; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR002716; PIN_dom.
DR   InterPro; IPR002792; TRAM_dom.
DR   SMART; SM00670; PINc; 1.
DR   SUPFAM; SSF88723; SSF88723; 1.
DR   PROSITE; PS50926; TRAM; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Metal-binding; Nuclease; Reference proteome.
FT   CHAIN           1..359
FT                   /note="Uncharacterized PIN and TRAM-domain containing
FT                   protein slr1972"
FT                   /id="PRO_0000217411"
FT   DOMAIN          163..275
FT                   /note="PINc"
FT   DOMAIN          289..350
FT                   /note="TRAM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00208"
FT   BINDING         165
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000255"
FT   BINDING         244
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   359 AA;  38815 MW;  113C7C8C8F4F2D93 CRC64;
     MLDAVIILLS IFTFAGVGFA VVDLLPDSVQ MQISNMEALR WLAAGFMSII GLAIGLVAQT
     TYRRLENQIR QTPIETILTR AVGLVIGLLI ANLMLAPIFL LPIPGEFSFI KPTLAVFGSV
     VFAFLGISLA DTHGRTFMRL INPNSIETML LAEGTLKPIP PKVVDTSCII DGRIEPLLAT
     GFIEGQVLVP QFVLAELQQL ADASNDQKRV RGRRGLDILG SIQADFPESI VIHSADYDDI
     ATVDAKLVHL AQEINGILLT NDYNLSKVAN LQKVQILNVN DLAQAVRPIY LPGDSLELKI
     IKQGKEASQG VGYLEDGTMV VVEEGRNYVG SELQVIVTSA LQTSAGRMIF AKPPSVLAS