ID   Y1978_STAA8             Reviewed;         374 AA.
AC   Q2FX99;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=UPF0754 membrane protein SAOUHSC_01978;
GN   OrderedLocusNames=SAOUHSC_01978;
OS   Staphylococcus aureus (strain NCTC 8325 / PS 47).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=93061;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 8325 / PS 47;
RA   Gillaspy A.F., Worrell V., Orvis J., Roe B.A., Dyer D.W., Iandolo J.J.;
RT   "The Staphylococcus aureus NCTC 8325 genome.";
RL   (In) Fischetti V., Novick R., Ferretti J., Portnoy D., Rood J. (eds.);
RL   Gram positive pathogens, 2nd edition, pp.381-412, ASM Press, Washington
RL   D.C. (2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0754 family. {ECO:0000305}.
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DR   EMBL; CP000253; ABD31037.1; -; Genomic_DNA.
DR   RefSeq; WP_000992527.1; NZ_LS483365.1.
DR   RefSeq; YP_500475.1; NC_007795.1.
DR   AlphaFoldDB; Q2FX99; -.
DR   STRING; 1280.SAXN108_1875; -.
DR   EnsemblBacteria; ABD31037; ABD31037; SAOUHSC_01978.
DR   GeneID; 3920454; -.
DR   KEGG; sao:SAOUHSC_01978; -.
DR   PATRIC; fig|93061.5.peg.1799; -.
DR   eggNOG; COG4399; Bacteria.
DR   HOGENOM; CLU_042384_0_0_9; -.
DR   OMA; DTIMGSL; -.
DR   PRO; PR:Q2FX99; -.
DR   Proteomes; UP000008816; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007383; DUF445.
DR   InterPro; IPR016991; UCP032178.
DR   Pfam; PF04286; DUF445; 1.
DR   PIRSF; PIRSF032178; UCP032178; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..374
FT                   /note="UPF0754 membrane protein SAOUHSC_01978"
FT                   /id="PRO_0000388314"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        354..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   374 AA;  42696 MW;  095EC493777FB6E4 CRC64;
     MNALFIIIFM IVVGAIIGGI TNVIAIRMLF HPFKPYYIFK FRVPFTPGLI PKRREEIATK
     IGQVIEEHLL TETLINEKLK SEQSQQAIES MIQQQLQKLT KDQLSIKQIT SQIDIDLEQV
     LQTNGNQYIE SQLNNYYTKH QNQTIASLLP NQLVTFLNQH VDNATDLLCD RARNYLSSAK
     GTQDINDMLD TFFNEKGKLI GMLQMFMTKE SIADRIQQEL IRLTSHPKAR TIVTSLITNE
     YQTFKDKPLN ELLDASQFNE IAENLSVYVT TYASKQANKP VVTLMPQFVD YLEGQLSSKL
     ANLIIEKLSI HLSTIMKKVD LRGLIEEQIN TFDLDYIEKL IIEIANKELK LIMSLGFILG
     GIIGFFQGLV AIFV