ID   Y1979_MYCTU             Reviewed;         481 AA.
AC   P9WQM5; L0T8F5; O53980; Q10875;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Uncharacterized transporter Rv1979c;
GN   OrderedLocusNames=Rv1979c; ORFNames=MTCY39.40, MTV051.17c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- FUNCTION: Probable amino-acid or metabolite transport protein.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC       superfamily. {ECO:0000305}.
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DR   EMBL; AL123456; CCP44748.1; -; Genomic_DNA.
DR   PIR; F70890; F70890.
DR   RefSeq; NP_216495.2; NC_000962.3.
DR   RefSeq; WP_003899115.1; NZ_NVQJ01000048.1.
DR   AlphaFoldDB; P9WQM5; -.
DR   SMR; P9WQM5; -.
DR   STRING; 83332.Rv1979c; -.
DR   PaxDb; P9WQM5; -.
DR   GeneID; 885819; -.
DR   KEGG; mtu:Rv1979c; -.
DR   TubercuList; Rv1979c; -.
DR   eggNOG; COG0531; Bacteria.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   Pfam; PF13520; AA_permease_2; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..481
FT                   /note="Uncharacterized transporter Rv1979c"
FT                   /id="PRO_0000054225"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        46..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        258..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        377..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        411..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        446..466
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   481 AA;  51116 MW;  50AEB190DC32B9D1 CRC64;
     MVGPRTRGYA IHKLGFCSVV MLGINSIIGA GIFLTPGEVI GLAGPFAPMA YVLAGIFAGV
     VAIVFATAAR YVRTNGASYA YTTAAFGRRI GIYVGVTHAI TASIAWGVLA SFFVSTLLRV
     AFPDKAWADA EQLFSVKTLT FLGFIGVLLA INLFGNRAIK WANGTSTVGK AFALSAFIVG
     GLWIITTQHV NNYATAWSAY SATPYSLLGV AEIGKGTFSS MALATIVALY AFTGFESIAN
     AAEEMDAPDR NLPRAIPIAI FSVGAIYLLT LTVAMLLGSN KIAASDDTVK LAAAIGNATF
     RTIIVVGALI SMFGINVAAS FGAPRLWTAL ADSGVLPTRL SRKNQYDVPM VSFAITASLA
     LAFPLALRFD NLHLTGLAVI ARFVQFIIVP IALIALARSQ AVEHAAVRRN AFTDKVLPLV
     AIVVSVGLAV SYDYRCIFLV RGGPNYFSIA LIVITFIVVP AMAYLHYYRI IRRVGDRPST
     R