ID   Y1980_STAAR             Reviewed;         328 AA.
AC   Q6GFG8;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=UPF0421 protein SAR1980;
GN   OrderedLocusNames=SAR1980;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0421 family. {ECO:0000305}.
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DR   EMBL; BX571856; CAG40966.1; -; Genomic_DNA.
DR   RefSeq; WP_001014423.1; NC_002952.2.
DR   AlphaFoldDB; Q6GFG8; -.
DR   SMR; Q6GFG8; -.
DR   KEGG; sar:SAR1980; -.
DR   HOGENOM; CLU_067028_0_0_9; -.
DR   OMA; ANVMEEW; -.
DR   OrthoDB; 1974930at2; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010343; ArAE_1.
DR   Pfam; PF06081; ArAE_1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..328
FT                   /note="UPF0421 protein SAR1980"
FT                   /id="PRO_0000283019"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        108..128
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   328 AA;  37378 MW;  0C576628AABC189F CRC64;
     MNGQWYKHLI GARTIKTGIA IFLTAVFCMA LDLTPIYAIL TAVVTIEPTA KASLIKGYRR
     LPATVIGAGF AVLFTYLFGD QSPFTYALSA TFTILFCTKL KLQVGTNVAV LTSLAMIPGI
     HDAYIFNFLS RTLTAIIGLV TSGLINFMVF PPKYYGQVEE KLSKTDALMY KLFYNRCQEI
     ILSRLQSDKS EKAYKNIFNL NNQVETLISY QRDELSYHKK KECDWKLLNQ LTKRAYTNRL
     FITHLSNIIY LPKNTRVNFS GDEKMALLKI SSSIKDIFYD GSFKREDDSV ETLRSTIKAL
     EISGENQIKS HILYEVLMIY RLLDSRYA