CAPTC_DICDI
ID CAPTC_DICDI Reviewed; 399 AA.
AC Q550W1; O15734;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-MAY-2006, sequence version 1.
DT 25-MAY-2022, entry version 78.
DE RecName: Full=Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein 3;
DE AltName: Full=Developmental gene 1056 protein;
GN Name=captC; Synonyms=DG1056, lipB; ORFNames=DDB_G0276763;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=AX4;
RA Loomis W.F., Iranfar N.;
RL Submitted (AUG-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CDP-alcohol phosphatidyltransferase class-I
CC family. {ECO:0000305}.
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DR EMBL; AF019108; AAB70818.1; -; Genomic_DNA.
DR EMBL; AAFI02000019; EAL68883.2; -; Genomic_DNA.
DR RefSeq; XP_642821.2; XM_637729.2.
DR AlphaFoldDB; Q550W1; -.
DR STRING; 44689.DDB0191335; -.
DR PaxDb; Q550W1; -.
DR EnsemblProtists; EAL68883; EAL68883; DDB_G0276763.
DR GeneID; 8620684; -.
DR KEGG; ddi:DDB_G0276763; -.
DR dictyBase; DDB_G0276763; captC.
DR eggNOG; KOG2877; Eukaryota.
DR HOGENOM; CLU_035066_0_1_1; -.
DR InParanoid; Q550W1; -.
DR OMA; PWGYDAS; -.
DR PhylomeDB; Q550W1; -.
DR PRO; PR:Q550W1; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1760; -; 1.
DR InterPro; IPR000462; CDP-OH_P_trans.
DR InterPro; IPR043130; CDP-OH_PTrfase_TM_dom.
DR InterPro; IPR014472; CHOPT.
DR PANTHER; PTHR10414; PTHR10414; 1.
DR Pfam; PF01066; CDP-OH_P_transf; 1.
DR PIRSF; PIRSF015665; CHOPT; 1.
DR PROSITE; PS00379; CDP_ALCOHOL_P_TRANSF; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..399
FT /note="Uncharacterized CDP-alcohol phosphatidyltransferase
FT class-I family protein 3"
FT /id="PRO_0000342199"
FT TRANSMEM 46..66
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 76..95
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 262..282
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 303..323
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 330..350
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 352..372
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 49
FT /note="Y -> N (in Ref. 1; AAB70818)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 399 AA; 45059 MW; 7D7228827F3E9A47 CRC64;
MNVVLSKSAL ENVSKHKYSG IDDSILAKLI LQKYWNFCLK FVPLNIAPYL ITLTGTITIL
LSFFIVGYYS PYLEGTLPRW VYAMSGLTLF FYQTMDNLDG KQARRTGSSS PLGQLFDHGC
DSIVCTLQSL IVASVANYGV GYISLIQLFI TALLPFWMAT WEEYHTGVLH LGPINGPDEG
IIIIVCALLS TAIFGNAFWT FKPFVASSQL LPSIIQQWLP TFIQQLMLNE IIVASLSLPC
LITCFFNIKN VVQHLQAKQK PILPALKHIL VWVIITVSSF IWYYTSTNLL PLSSIWFNNI
RTVQFSIGII FGELVSRLIL AHMCHEKYNI IQAPLYPLIL STFCSTINYF NGTIIIPENL
LLILFTVTSF VHYSLFVKST ISQLCSYLNI KCFTITKKH
