ID   Y1987_MYCUA             Reviewed;         282 AA.
AC   A0PQ11;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Uncharacterized oxidoreductase MUL_1987;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=MUL_1987;
OS   Mycobacterium ulcerans (strain Agy99).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=362242;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Agy99;
RX   PubMed=17210928; DOI=10.1101/gr.5942807;
RA   Stinear T.P., Seemann T., Pidot S., Frigui W., Reysset G., Garnier T.,
RA   Meurice G., Simon D., Bouchier C., Ma L., Tichit M., Porter J.L., Ryan J.,
RA   Johnson P.D.R., Davies J.K., Jenkin G.A., Small P.L.C., Jones L.M.,
RA   Tekaia F., Laval F., Daffe M., Parkhill J., Cole S.T.;
RT   "Reductive evolution and niche adaptation inferred from the genome of
RT   Mycobacterium ulcerans, the causative agent of Buruli ulcer.";
RL   Genome Res. 17:192-200(2007).
CC   -!- SIMILARITY: Belongs to the aldo/keto reductase family. {ECO:0000305}.
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DR   EMBL; CP000325; ABL04430.1; -; Genomic_DNA.
DR   RefSeq; WP_011740049.1; NC_008611.1.
DR   AlphaFoldDB; A0PQ11; -.
DR   SMR; A0PQ11; -.
DR   STRING; 362242.MUL_1987; -.
DR   EnsemblBacteria; ABL04430; ABL04430; MUL_1987.
DR   KEGG; mul:MUL_1987; -.
DR   eggNOG; COG0656; Bacteria.
DR   HOGENOM; CLU_023205_0_1_11; -.
DR   OMA; KLWPTDQ; -.
DR   Proteomes; UP000000765; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.100; -; 1.
DR   InterPro; IPR020471; AKR.
DR   InterPro; IPR018170; Aldo/ket_reductase_CS.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR43827; PTHR43827; 1.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   PIRSF; PIRSF000097; AKR; 1.
DR   PRINTS; PR00069; ALDKETRDTASE.
DR   SUPFAM; SSF51430; SSF51430; 1.
DR   PROSITE; PS00062; ALDOKETO_REDUCTASE_2; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..282
FT                   /note="Uncharacterized oxidoreductase MUL_1987"
FT                   /id="PRO_0000380749"
FT   ACT_SITE        57
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250"
FT   BINDING         115
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   BINDING         195..247
FT                   /ligand="NADP(+)"
FT                   /ligand_id="ChEBI:CHEBI:58349"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   282 AA;  29948 MW;  2D93B4D9ADB03981 CRC64;
     MMPGAPSPSA PSIALNDENT MPVLGMGVAG LSDDETERAV SAALEIGCRL IDTAAAYGNE
     AAVGRALAAS GIPRAELFVT TKVATADHGF TASREACKAS LDRLGLDYVD LYLIHWPAPA
     VGKYVDAFGG LIQARGEGFT RSIGVSNFTE EHVSNVIDLT FVTPAVNQVE LHPLLNQDEL
     RKANAQHNVV TQSYTPLALG QLADNPTVTS IAGEYGKTPT QVLLRWNLQL GNAVIFGSSN
     AEHIVTNLDV FEFELASQHM DAINGLNDGT RLREDPMTFA GV