CAPTD_DICDI
ID CAPTD_DICDI Reviewed; 379 AA.
AC Q8T2Q6; Q554J0;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Uncharacterized CDP-alcohol phosphatidyltransferase class-I family protein 4;
GN Name=captD; ORFNames=DDB_G0275235;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CDP-alcohol phosphatidyltransferase class-I
CC family. {ECO:0000305}.
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DR EMBL; AAFI02000013; EAL69898.1; -; Genomic_DNA.
DR RefSeq; XP_643721.1; XM_638629.1.
DR AlphaFoldDB; Q8T2Q6; -.
DR STRING; 44689.DDB0266713; -.
DR PaxDb; Q8T2Q6; -.
DR EnsemblProtists; EAL69898; EAL69898; DDB_G0275235.
DR GeneID; 8619761; -.
DR KEGG; ddi:DDB_G0275235; -.
DR dictyBase; DDB_G0275235; captD.
DR eggNOG; KOG2877; Eukaryota.
DR HOGENOM; CLU_035066_5_2_1; -.
DR InParanoid; Q8T2Q6; -.
DR OMA; MGITESH; -.
DR PhylomeDB; Q8T2Q6; -.
DR Reactome; R-DDI-1483191; Synthesis of PC.
DR Reactome; R-DDI-1483213; Synthesis of PE.
DR PRO; PR:Q8T2Q6; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016780; F:phosphotransferase activity, for other substituted phosphate groups; IEA:InterPro.
DR GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1760; -; 1.
DR InterPro; IPR000462; CDP-OH_P_trans.
DR InterPro; IPR043130; CDP-OH_PTrfase_TM_dom.
DR InterPro; IPR014472; CHOPT.
DR PANTHER; PTHR10414; PTHR10414; 1.
DR Pfam; PF01066; CDP-OH_P_transf; 1.
DR PIRSF; PIRSF015665; CHOPT; 1.
DR PROSITE; PS00379; CDP_ALCOHOL_P_TRANSF; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transferase; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..379
FT /note="Uncharacterized CDP-alcohol phosphatidyltransferase
FT class-I family protein 4"
FT /id="PRO_0000342200"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 241..261
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 268..288
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 308..328
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 333..353
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 379 AA; 43303 MW; D5267F8CC7F95ABE CRC64;
MVYITPKGKI NLPNYKGGTT IDKSIMYQYI TAIGLFCNFL GLFSVFYFIG FNESIGGNKP
TLEDDSSVRW VYLFAGMMIF IYMMMDNIDG KQARRTKTSS PLGELFDHGC DSLCTGLLPL
IVGISMGIRS WEILIAFMAA TIPFYLAHWE EYFTHHLVLG ALNGPTEAEC MAILFCFLTG
IFGQWIWFIK IDFSVLTFNH IQYTGQLNEM IFFAMAIISF VTAFQNILTS TKKAIDMKIS
LFTAYSQPIP FIIFFCSEFI WLKLSPSLFL TYPIIHILSL TFIFSYVVCR CIVQRICQED
FRLFYKPLIF LIGCVLNTAA KVYLNIEILD EQISVLLLFA ISLGFMFHFT YSIIQEMCLV
LKINAFTIPS SSPPIKKLN
