ID   Y1989_PYRHO             Reviewed;         335 AA.
AC   O57713;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=UPF0104 membrane protein PH1989;
GN   OrderedLocusNames=PH1989;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0104 family. {ECO:0000305}.
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DR   EMBL; BA000001; BAA31116.1; -; Genomic_DNA.
DR   PIR; E71215; E71215.
DR   RefSeq; WP_010886051.1; NC_000961.1.
DR   AlphaFoldDB; O57713; -.
DR   SMR; O57713; -.
DR   STRING; 70601.3258433; -.
DR   EnsemblBacteria; BAA31116; BAA31116; BAA31116.
DR   GeneID; 1442833; -.
DR   KEGG; pho:PH1989; -.
DR   eggNOG; arCOG00899; Archaea.
DR   OMA; WFGECAA; -.
DR   OrthoDB; 36454at2157; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR022791; L-PG_synthase/AglD.
DR   Pfam; PF03706; LPG_synthase_TM; 1.
DR   TIGRFAMs; TIGR00374; TIGR00374; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..335
FT                   /note="UPF0104 membrane protein PH1989"
FT                   /id="PRO_0000138109"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        266..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   335 AA;  37503 MW;  95745BC337B7B494 CRC64;
     MKKYLLIIIG VTLVLILLWW AGIERTIKLM MRADIRFILL AILMYCISVL IWAVRWNTFL
     KGANINVSFV KVIEGVFIGI FLNNLTPGAR TGGEAVKVIF IKKASSNGSY SKVFATVIAD
     RILDVIPVVV FMMLAFLYAL TIHARVLLII LGISAIILVI ILLMTTVFSI KEKYALSALL
     YLARIFRKIF PSKFSMSEDK IKEKLLGEIR EFKETFLRLA KRKRRLSSTM LYSFILWGAD
     ILKTYFIFLS LGGRITFLQV LLVRMASIAV AMISVIPGGI GITEVVQSAL FLAVGVEKAL
     AVSVTMLDRL ISFWIPTLLG GILVLKNRKL LVSSS