ID   Y1993_PSEAE             Reviewed;         402 AA.
AC   Q9I2B6;
DT   10-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Uncharacterized MFS-type transporter PA1993 {ECO:0000255|HAMAP-Rule:MF_01118};
GN   OrderedLocusNames=PA1993;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01118}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01118}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. YhhS family.
CC       {ECO:0000255|HAMAP-Rule:MF_01118}.
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DR   EMBL; AE004091; AAG05381.1; -; Genomic_DNA.
DR   PIR; A83398; A83398.
DR   RefSeq; NP_250683.1; NC_002516.2.
DR   RefSeq; WP_003113497.1; NZ_QZGE01000026.1.
DR   AlphaFoldDB; Q9I2B6; -.
DR   SMR; Q9I2B6; -.
DR   STRING; 287.DR97_5854; -.
DR   PaxDb; Q9I2B6; -.
DR   EnsemblBacteria; AAG05381; AAG05381; PA1993.
DR   GeneID; 880155; -.
DR   KEGG; pae:PA1993; -.
DR   PATRIC; fig|208964.12.peg.2077; -.
DR   PseudoCAP; PA1993; -.
DR   HOGENOM; CLU_001265_10_3_6; -.
DR   InParanoid; Q9I2B6; -.
DR   OMA; CAFVGAR; -.
DR   PhylomeDB; Q9I2B6; -.
DR   BioCyc; PAER208964:G1FZ6-2031-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   HAMAP; MF_01118; MFS_YhhS; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR023008; MFS_YhhS-like.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..402
FT                   /note="Uncharacterized MFS-type transporter PA1993"
FT                   /id="PRO_0000087806"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        228..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        309..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        351..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
FT   TRANSMEM        375..395
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01118"
SQ   SEQUENCE   402 AA;  41455 MW;  B963D54719F32DEC CRC64;
     MSVDIRPTPP AQDSARQNVT LQIVSVVMFT FIGYLTIGIP LAVLPGYVHD DLGYGSVLAG
     LVISLQYLAT LLARPYAGRV IDGLGPKRAV LYGMAGSAAS GLFMLLSVAI QGWPALSLAS
     LLVGRLVLGA AESLVGSAAI GWGIGRVGAP HTAKVISWNG IASYGAIALG APLGVLLVQW
     LGLWSMGASI VLLGALGFAL AWPKLPAPLV HGERLPFHHV LGRVTPHGMG LALGAIGFGT
     IATFITLYYA SRGWANAVLC LSAFGGCFIG ARLLFANSIN RLGGFRVAII CLGVESLGLL
     LLWSAPNPWV GLAGAALTGF GFSLVFPAFG VEAVNLVPAS NRGAALGAYS LFVDLSLGIT
     GPLVGFVANL FGFRSMFLFA CLASLGGLAL AVALHRRSRR PG